Kokubo Toshio

コクボトシオ | Kokubo Toshio

Affiliation and department：
Job title： Professor

Research field (4)： Molecular biology , Cell biology , Pharmaceuticals - chemistry and drug development , Clinical pharmacy

Research theme for competitive and other funds (1)：

2015 - 2020 Development of a new sleep-wake control method for super stress environment, Space

Papers (24)：

Zhang, Simeng, Takano, Jiro, Murayama, Norihito, Tominaga, Morie, Abe, Takashi, Park, Insung, Seol, Jaehoon, Ishihara, Asuka, Tanaka, Yoshiaki, Yajima, Katsuhiko, et al. Subacute Ingestion of Caffeine and Oolong Tea Increases Fat Oxidation without Affecting Energy Expenditure and Sleep Architecture: A Randomized, Placebo-Controlled, Double-Blinded Cross-Over Trial. Nutrients. 2020. 12. 12. 3671-3671
Seol, J, Fujii, Y, Park, I, Yoko, S, Kawana, F, Yajima, K, Fukusumi, S, Okura, T, Satoh, M, Tokuyama, K, et al. DIFFERENT EFFECTS OF OREXIN RECEPTOR ANTAGONIST AND GABA(A) AGONIST ON PHYSICAL AND COGNITIVE FUNCTIONS AFTER FORCED AWAKENING. SLEEP MEDICINE. 2019. 64. 1. S343-S343
Kokubo, Toshio, Kayaba, M, Ogata, H, Park, I, Ishihara, A, Kawana, F, Fukusumi, S, Hayashi, M, Tokuyama, K, Yanagisawa, M, et al. Improvement of slow wave sleep continuity by mattress with better body pressure dispersal. Sleep Medicine Research. 2019. 10. 2. 75-82
Seol, Jaehoon, Fujii, Yuya, Park, Insung, Suzuki, Yoko, Kawana, Fusae, Yajima, Katsuhiko, Fukusumi, Shoji, Okura, Tomohiro, Satoh, Makoto, Tokuyama, Kumpei, et al. Distinct effects of orexin receptor antagonist and GABA agonist on sleep and physical/cognitive functions after forced awakening. Proceedings of the National Academy of Sciences of the United States of America. 2019. 116. 48. 24353-24358
Oshima, Tsutomu, Miyashita, Hideaki, Ishimura, Yoshimasa, Ito, Yuki, Tanaka, Yoko, Hori, Akira, Kokubo, Toshio, Kurokawa, Tomofumi. Fc engineering of anti-Nectin-2 antibody improved thrombocytopenic adverse event in monkey. PLOS ONE. 2018. 13. 5

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Books (2)：

Molecular and Cellular Biology of Bone
JAI Press 1998
Development of Some Reactions Controlled in Molecular Assemblies
1983

Lectures and oral presentations (1)：

Different effects of orexin receptor antagonist and GABAa agonist on physical and cognitive functions
(The 7th Annual IIIS Symposium 2018)

Education (3)：

1980 - 1983 京都大学大学院工学研究科合成化学専攻
1978 - 1980 京都大学大学院工学研究科合成化学専攻
1974 - 1978 京都大学工学部合成化学

Professional career (1)：

工学博士(京都大学) (京都大学)

Work history (12)：

2013/06 - 現在筑波大学国際統合睡眠医科学研究機構教授/事務部門長
2013/02 - 2013/05 筑波大学国際統合睡眠医科学研究機構教授/副事務部門長
2011/04 - 2013/01 武田薬品工業(株) 医薬研究本部アライアンス室主席部員
2010/04 - 2011/03 武田薬品工業(株) 医薬研究本部筑波研究推進グループグループマネジャー
2005/12 - 2010/03 武田薬品工業(株) 医薬研究本部バイオ医薬研究室室長

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