Rchr
J-GLOBAL ID:202101003018622052
Update date: Sep. 13, 2024
Yamamoto Mizuki
ヤマモト ミズキ | Yamamoto Mizuki
Affiliation and department:
Research field (2):
Virology
, Tumor biology
Research keywords (6):
SARS-CoV-2
, enveloped virus
, membrane fusion
, Zika virus
, Dengue virus
, breast cancer
Research theme for competitive and other funds (12):
- 2023 - 2026 SARS-CoV-2のメタロプロテアーゼ依存性感染機構の解析
- 2022 - 2025 病態解析に基づいたウイルス性呼吸器感染症に有効なTMPRSS2 阻害薬の開発
- 2022 - 2025 デング・ジカウイルスの膜融合阻害による感染阻害薬の創出
- 2021 - 2024 亜熱帯生物素材ライブラリの活用によるウイルス感染症に対する天然物創薬研究
- 2020 - 2023 Genome-wide screening for EMT-MET plasticity in triple-negative breast cancer
- 2022 - 2023 多様な変異株に有効な新型コロナウイルス中和抗体の中和機構の解析
- 2016 - 2021 Spatiotemporal regulation of Inflammation and immune signals by ubiquitination and its mathematical simulation
- 2018 - 2020 Genome-wide screening for epithelial mesenchymal transition (EMT)-related genes in triple-negative breast cancer
- 2015 - 2017 Analysis of mechanisms of breast cancer stem cells using mammary tumor model mice
- 2014 - 2017 Molecular mechanisms of maintenance of cancer stem cells in malignant breast cancers
- 2012 - 2015 初代乳腺上皮細胞の三次元培養システムの開発とその高悪性乳癌発症機構解析への応用
- 2010 - 2011 乳癌幹細胞におけるNF-kappaB活性化の解析
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Papers (38):
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Tatsuo Adachi, Shigetaka Nakamura, Akiya Michishita, Daiki Kawahara, Mizuki Yamamoto, Michiaki Hamada, Yoshikazu Nakamura. RaptGen-Assisted Generation of an RNA/DNA Hybrid Aptamer against SARS-CoV-2 Spike Protein. Biochemistry. 2024
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Ahmed H. E. Hassan, Selwan M. El-Sayed, Mizuki Yamamoto, Jin Gohda, Takehisa Matsumoto, Mikako Shirouzu, Jun-ichiro Inoue, Yasushi Kawaguchi, Reem M. A. Mansour, Abtin Anvari, et al. In Silico and In Vitro Evaluation of Some Amidine Derivatives as Hit Compounds towards Development of Inhibitors against Coronavirus Diseases. Viruses. 2023
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Yusuke Hayashi, Jun Nakayama, Mizuki Yamamoto, Masashi Maekawa, Shinya Watanabe, Shigeki Higashiyama, Jun-Ichiro Inoue, Yusuke Yamamoto, Kentaro Semba. Aberrant accumulation of NIK promotes tumor growth by dysregulating translation and post-translational modifications in breast cancer. Cancer cell international. 2023. 23. 1. 57-57
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Tadashi Yamamoto, Miho Tokumasu, Atsuko Sato, Taku Ito-Kureha, Mizuki Yamamoto, Nao Ohmine, Kentaro Semba, Jun-ichiro Inoue. Tob negatively regulates NF-κB activation in breast cancer through its association with the TNF receptor complex. 2023
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Yasuhiro Hayashi, Xuhao Huang, Takashi Tanikawa, Kazunari Tanigawa, Mizuki Yamamoto, Jin Gohda, Jun-Ichiro Inoue, Koichi Fukase, Kazuya Kabayama. Reactive oxygen species are associated with the inhibitory effect of N-(4-hydroxyphenyl)-retinamide on the entry of the severe acute respiratory syndrome-coronavirus 2. Journal of biochemistry. 2023
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MISC (9):
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林 祐介, 中山 淳, 山本 瑞生, 井上 純一郎, 山本 雄介, 仙波 憲太郎. 同所性乳がん高転移株におけるNIKの機能解析. 日本癌学会総会記事. 2021. 80回. [J10-2]
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林祐介, 林祐介, 中山淳, 中山淳, 山本瑞生, 井上純一郎, 山本雄介, 仙波憲太郎, 仙波憲太郎. Signal analysis of lung metastatic breast cancer cell established by orthotopic xenograft. 日本分子生物学会年会プログラム・要旨集(Web). 2021. 44th
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山本瑞生. COVID-19 drug development. 月刊臨床免疫・アレルギー科. 2021. 75. 2
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山本瑞生, 合田仁. Drug repositioning for emerging and re-emerging infectious diseases. 実験医学. 2021. 39. 2
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山本瑞生. COVID-19病態と対応 SARS-CoV-2とプロテアーゼ阻害薬. Thrombosis Medicine. 2021. 11. 2
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Education (3):
- 2008 - 2012 The University of Tokyo Graduate School of Medicine
- 2006 - 2008 Keio University Graduate School of Science and Technology
- 2002 - 2006 Keio University Faculty of Science and Technology Department of Applied Chemistry
Work history (3):
- 2020/04 - 現在 The University of Tokyo The Institute of Medical Science
- 2015/04 - 2020/03 The University of Tokyo The Institute of Medical Science
- 2012/04 - 2015/03 Waseda University School of Advanced Science and Engineering
Awards (4):
- 2021/10 - 第80回日本癌学会学術総会 若手研究者ポスター賞
- 2021/05 - 東京大学医科学研究所 2021年度医科学研究所研究成果発表会
- 2018/10 - Cancer Science Young Scientists Award
- 2005/03 - 慶応義塾大学理工学部応用化学科 第一回慶應義塾応用化学進歩賞
Association Membership(s) (3):
分子生物学会
, 日本ウイルス学会
, 日本癌学会
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