Rchr
J-GLOBAL ID：202101008552134952
Update date: Feb. 01, 2024
HAYASHI YASUTAKA
ハヤシ ヤスタカ | HAYASHI YASUTAKA
Affiliation and department：
Research field (3)：
Cell biology
, Cell biology
, Hematology and oncology
Research keywords (3)：
間葉系幹細胞
, 骨髄微小環境
, 造血幹細胞
Research theme for competitive and other funds (2)：
- 2021 - 2024 間葉系幹細胞の分化異常が引き起こす造血不全の病態解析
- 2020 - 2023 造血器腫瘍における細胞外小胞の動態解析と治療応用
Papers (14)：
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Yasutaka Hayashi, Koutarou Nishimura, Atsushi Tanaka, Daichi Inoue. Extracellular vesicle-mediated remodeling of the bone marrow microenvironment in myeloid malignancies. International journal of hematology. 2023
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Atsushi Tanaka, Taizo A Nakano, Masaki Nomura, Hiromi Yamazaki, Jan Philipp Bewersdorf, Roger Mulet-Lazaro, Simon Hogg, Bo Liu, Alex Vincent Penson, Akihiko Yokoyama, et al. Aberrant EVI1 splicing contributes to EVI1-rearranged leukemia. Blood. 2022. 140. 8. 875-888
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Yasutaka Hayashi, Kimihito C Kawabata, Yosuke Tanaka, Yasufumi Uehara, Yo Mabuchi, Koichi Murakami, Akira Nishiyama, Shigeru Kiryu, Yusuke Yoshioka, Yasunori Ota, et al. MDS cells impair osteolineage differentiation of MSCs via extracellular vesicles to suppress normal hematopoiesis. Cell reports. 2022. 39. 6. 110805-110805
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Daichi Inoue, Jacob T Polaski, Justin Taylor, Pau Castel, Sisi Chen, Susumu Kobayashi, Simon J Hogg, Yasutaka Hayashi, Jose Mario Bello Pineda, Ettaib El Marabti, et al. Minor intron retention drives clonal hematopoietic disorders and diverse cancer predisposition. Nature genetics. 2021. 53. 5. 707-718
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Reina Takeda, Shuhei Asada, Sung-Joon Park, Akihiko Yokoyama, Hans Jiro Becker, Akinori Kanai, Valeria Visconte, Courtney Hershberger, Yasutaka Hayashi, Taishi Yonezawa, et al. HHEX promotes myeloid transformation in cooperation with mutant ASXL1. Blood. 2020. 136. 14. 1670-1684
ｍore...
MISC (5)：
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Yasutaka Hayashi, Kimihito Cojin Kawabata, Yosuke Tanaka, Yasufumi Uehara, Shigeru Kiryu, Yasunori Ota, Yusuke Yoshioka, Yo Mabuchi, Tatsuki Sugiyama, Keiko Mikami, et al. Impaired Osteoblastic Differentiation of MSCs Suppresses Normal Hematopoiesis in MDS. BLOOD. 2020. 136
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Susumu Goyama, Shiori Shikata, Yasutaka Hayashi, Yuto Izawa, Janet Schibler, Hiroyuki Iwamura, Motoki Saito, Satoshi Kofuji, Kazutaka Sumita, Atsuo T. Sasaki, et al. Inhibition of Impdh As an Effective Treatment for MLL-Fusion Leukemia. BLOOD. 2016. 128. 22
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Kimihito Cojin Kawabata, Yasutaka Hayashi, Daichi Inoue, Hiroki Mizuno, Jiro Kitaura, Yosuke Tanaka, Susumu Goyama, Yuka Harada, Hironori Harada, Hiroyuki Aburatani, et al. HIGHER EXPRESSION OF ATP-BINDING CASSETTE TRANSPORTER G2 (ABCG2) IS SPECIFIC TO ADVANCED MDS AND PROMOTES INEFFICIENT HEMATOPIESIS VIA CONVERSIONS OF TUMOR MICROENVIRONMENTS IN MOUSE BONE MARROW TRANSPLANTATION MODEL. EXPERIMENTAL HEMATOLOGY. 2016. 44. 9. S110-S110
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Daichi Inoue, Hirotaka Matsui, Hsin-An Hou, Wen-Chien Chou, Akiko Nagamachi, Jiro Kitaura, Kimihito Cojin Kawabata, Katsuhiro Togami, Reina Nagase, Sayuri Horikawa, et al. SETBP1 Mutations Drive Leukemic Transformation in ASXL1-Mutated MDS. BLOOD. 2014. 124. 21
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北村 俊雄, 井上 大地, 中原 史雄, 大河内 直子, 加藤 奈緒子, 戸上 勝仁, 内田 智之, 鍵山 侑希, 川畑 公人, 永瀬 玲奈, et al. 骨髄系造血器腫瘍発症の分子機構. 臨床血液. 2014. 55. 10. 1715-1723
Education (2)：
- 2014 - 2018 The University of Tokyo Graduate School of Medicine
- 2008 - 2014 Kyushu University School of Medicine
Work history (3)：
- 2020/04 - 現在 公益財団法人 神戸医療産業都市推進機構 先端医療研究センター 血液・腫瘍研究部 日本学術振興会特別研究員
- 2019/05 - 2020/03 公益財団法人 神戸医療産業都市推進機構 先端医療研究センター 血液・腫瘍研究部 研究員
- 2018/04 - 2019/05 The University of Tokyo The Institute of Medical Science The Advanced Clinical Research Center Division of Cellular Therapy
Association Membership(s) (4)：
日本細胞外小胞学会
, 日本免疫学会
, 日本血液学会
, 日本分子生物学会
