Rchr
J-GLOBAL ID：202101011528077337
Update date: Feb. 01, 2024
Sakane Sadatsugu
サカネ サダツグ | Sakane Sadatsugu
Affiliation and department：
Job title：
Post-doc scholar
Other affiliations (1)：
Research theme for competitive and other funds (4)：
- 2022 - 2025 The mechanism of alcohol-associated hepatitis with obesity via adipose tissue-liver crosstalk
- 2020 - 2022 The role of omega-6 fatty acid metabolism in non-alcoholic steatohepatitis
- 2018 - 2020 Targeting autophagy to improve alcoholic liver disease
- 2014 - 2018 The impact of hepatocyte apoptosis and autophagy in the process of livercarcinogenesis
Papers (24)：
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Hyun Young Kim, Sadatsugu Sakane, Alvaro Eguileor, Raquel Carvalho Gontijo Weber, Wonseok Lee, Xiao Liu, Kevin Lam, Kei Ishizuka, Sara Brin Rosenthal, Karin Diggle, et al. The origin and fate of liver myofibroblasts. Cellular and molecular gastroenterology and hepatology. 2023
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Xiao Liu, Kevin Lam, Huayi Zhao, Sadatsugu Sakane, Hyun Young Kim, Alvaro Eguileor, Karin Diggle, Shuai Wu, Raquel Carvalho Gontijo Weber, Pejman Soroosh, et al. Isolation of primary human liver cells from normal and nonalcoholic steatohepatitis livers. STAR protocols. 2023. 4. 3. 102391-102391
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Yuki Makino, Hayato Hikita, Seiya Kato, Masaya Sugiyama, Minoru Shigekawa, Tatsuya Sakamoto, Yoichi Sasaki, Kazuhiro Murai, Sadatsugu Sakane, Takahiro Kodama, et al. STAT3 is Activated by CTGF-mediated Tumor-stroma Cross Talk to Promote HCC Progression. Cellular and molecular gastroenterology and hepatology. 2022. 15. 1. 99-119
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Katsuhiko Sato, Hayato Hikita, Minoru Shigekawa, Seiya Kato, Yoichi Sasaki, Kazuma Shinkai, Makoto Fukuoka, Shinnosuke Kudo, Yu Sato, Kenji Fukumoto, et al. PTX3 Is an Adipose Tissue-Related Serum Marker for Pancreatic Cancer Cachexia Predicting Subsequent Muscle Mass and Visceral Fat Loss. Cancer science. 2022. 113. 12. 4311-4326
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Yuki Makino, Hayato Hikita, Kenji Fukumoto, Ji Hyun Sung, Yoshihiro Sakano, Kazuhiro Murai, Sadatsugu Sakane, Takahiro Kodama, Ryotaro Sakamori, Jumpei Kondo, et al. Constitutive activation of the tumor suppressor p53 in hepatocytes paradoxically promotes non-cell autonomous liver carcinogenesis. Cancer research. 2022. 82. 16. 2860-2873
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MISC (92)：
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Kenji Fukumoto, Hayato Hikita, Sadatsugu Sakane, Kazuhiro Murai, Takahiro Kodama, Ryotaro Sakamori, Tomohide Tatsumi, Tetsuo Takehara. LYSOSOMAL DYSFUNCTION IN LIVER MACROPHAGES CONTRIBUTES TO NASH PATHOGENESIS. HEPATOLOGY. 2022. 76. S626-S627
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Sadatsugu Sakane, Hayato Hikita, Kumiko Shirai, Ryohei Narumi, Jun Adachi, Ryotaro Sakamori, Naruyasu Kakita, Yukinori Yamada, Tatsuya Sakamoto, Machiko Kai, et al. SERUM Fibulin3 IS A NOVEL FIBROSIS MARKER IN NAFLD REVEALED BY PROTEOMIC ANALYSIS OF SERUM EXTRACELLULAR VESICLES. HEPATOLOGY. 2022. 76. S801-S801
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坂根 貞嗣, 阪森 亮太郎, 竹原 徹郎. 栄養代謝性肝疾患のマネジメント-栄養・運動・新規治療・発がんリスク 非アルコール性脂肪性肝疾患におけるFadslの意義. 肝臓. 2022. 63. Suppl.1. A40-A40
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坂根 貞嗣, 巽 智秀, 竹原 徹郎. NAFLD/NASH診療-全身疾患としての位置づけ 非アルコール性脂肪性肝疾患における脂肪組織オートファジー抑制による肝病態改善機序の解明. 肝臓. 2022. 63. Suppl.1. A54-A54
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坂根貞嗣, 疋田隼人, 白井久美子, 竹原徹郎. Ethanol exposure in obesity induces hepatic injury via altered lipid metabolism. アルコール医学生物学研究会学術集会プログラム・抄録集(Web). 2022. 41st
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Awards (5)：
- 2022/10 - The Japan Society of Hepatology 冠Award (第7回 Gilead Sciences Award)
- 2022/02 - 第41回アルコール医学生物学研究会学術集会 優秀演題賞
- 2020/09 - Kansai Liver Club 2020 Best Presentation Award
- 2018/07 - The 5th Liver, Diabetes and Metabolism Forum Young investigator award
- 2017/10 - American Association for the Study of Liver Diseases (AASLD) Basic Science Young Investigator Travel Award
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