Rchr
J-GLOBAL ID：202101011579106960
Update date: Nov. 22, 2024
IMAI MOTOKI
イマイ モトキ | IMAI MOTOKI
Affiliation and department：
Job title：
Assistant Professor
Research field (3)：
Pathobiochemistry
, Laboratory animal science
, Tumor biology
Research keywords (4)：
診断マーカー
, 分子病理学
, リン酸化
, シグナル伝達
Papers (13)：
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Moragot Chatatikun, Hiroko P. Indo, Motoki Imai, Fumitaka Kawakami, Makoto Kubo, Yoshimasa Kitagawa, Hiroshi Ichikawa, Lunla Udomwech, Atthaphong Phongphithakchai, Orawan Sarakul, et al. Potential of traditional medicines in alleviating COVID-19 symptoms. Frontiers in Pharmacology. 2024. 15
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Fumitaka Kawakami, Motoki Imai, Yuki Isaka, Mark R. Cookson, Hiroko Maruyama, Makoto Kubo, Matthew J. Farrer, Makoto Kanzaki, Rei Kawashima, Tatsunori Maekawa, et al. LRRK2 negatively regulates glucose tolerance via regulation of membrane translocation of GLUT4 in adipocytes. FEBS Open Bio. 2023
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Fumitaka Kawakami, Motoki Imai, Shun Tamaki, Etsuro Ohta, Rei Kawashima, Tatsunori Maekawa, Yoshifumi Kurosaki, Kenichi Ohba, Takafumi Ichikawa. Nrf2 Expression Is Decreased in LRRK2 Transgenic Mouse Brain and LRRK2 Overexpressing SH-SY5Y Cells. Biological & pharmaceutical bulletin. 2023. 46. 1. 123-127
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Cho L. Aung, Fumitaka Kawakami, Motoki Imai, Thet-Thet Lwin, Makoto Kanzaki, Ohn Mar, Khin P. Phyu, Mya M. Thwin, Hiroko Maruyama. Blood glucose-lowering effect of water and ethanolic extracts of Gynura procumbens (Lour.) Merr. Traditional & Kampo Medicine. 2021. 8. 2. 138-147
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Motoki Imai, Fumitaka Kawakami, Makoto Kubo, Makoto Kanzaki, Hiroko Maruyama, Rei Kawashima, Tatsunori Maekawa, Yoshifumi Kurosaki, Fumiaki Kojima, Takafumi Ichikawa. LRRK2 Inhibition Ameliorates Dexamethasone-Induced Glucose Intolerance via Prevents Impairment in GLUT4 Membrane Translocation in Adipocytes. Biological and Pharmaceutical Bulletin. 2020. 43. 11. 1660-1668
ｍore...
MISC (1)：
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今井 基貴, 川上 文貴, 井阪 勇輝, 川島 麗, 前川 達則, 神崎 展. 脂肪組織における糖代謝に対するLRRK2の生理的役割の解析. 日本生化学会大会プログラム・講演要旨集. 2019. 92回. [1P-300]
Lectures and oral presentations (16)：
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Investigation of the physiological role of LRRK2 in glucose metabolism using dexamethasone-induced insulin resistance model
(2021)
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LRRK2を介したRabのリン酸化は脂肪組織における糖代謝を調節する
(第61回日本神経学会学術大会 2020)
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The mechanism of GLUT4 membrane translocation through the LRRK2-Rab pathway.
(第42回日本分子生物学会 2019)
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ワカメ添加高脂肪食がTau蛋白質のリン酸化およびβアミロイドの蓄積に及ぼす影響
(第37回日本肥満症治療学会 2019)
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The investigation of physiological role of LRRK2 in glucose metabolism in the adipocytes.
(第91回日本生化学大会 2019)
ｍore...
Education (3)：
- 2018 - 2021 Kitasato University Graduate School of Medical Sciences
- 2016 - 2018 Kitasato University Graduate School of Medical Sciences
- 2012 - 2016 Kitasato University School of Allied Health Sciences
Work history (1)：
- 2021/04 - 現在 北里大学 医療衛生学部 臨床検査学科 助教
Awards (2)：
- 2021/07 - ファイザー賞 Social behavior, neuroimmune markers and glutamic acid decarboxylase levels in a rat model of valproic acid-induced autism
- 2021/04 - 日本薬学会141年会 学生優秀発表賞 (口頭発表の部) Dexamethasone誘導インスリン抵抗性モデルを用いた糖代謝における LRRK2の生理的役割の解析
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