Rchr
J-GLOBAL ID：202101012702854271   Update date: May. 20, 2024

Maruyama Keiko

マルヤマ ケイコ | Maruyama Keiko
Affiliation and department：
National Cerebral and Cardiovascular Center, Research Institute

About National Cerebral and Cardiovascular Center, Research Institute


Research field  (1)： Hematology and oncology
Research keywords  (1)： 血液凝固
Research theme for competitive and other funds  (8)：
  • 2023 - 2026 凝固第V因子改変体を用いた新たなプロテインSおよびプロテインC活性検査法の確立
  • 2023 - 2024 Pros1イントロン1欠失マウスを用いたプロテインS発現調節機構の解明
  • 2022 - 2023 Protein S遺伝子のイントロン1に潜む未知の発現調節機構の解明
  • 2020 - 2023 血液凝固制御因子プロテインSおよびプロテインCの活性測定法の開発
  • 2022 - 血栓形成抑制に重要な働きをするプロテインSの新たな発現調節機構の解明
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Papers (13)：
  • Keiko Maruyama, Shigeki Miyata, Koichi Kokame. Alpha-HIT assay: A new assay for heparin-induced thrombocytopenia antibody detection using FcγRIIa-coated beads and Alpha technology. Research and Practice in Thrombosis and Haemostasis. 2022. 6. 7
  • Satomi Nagaya, Keiko Maruyama, Atsushi Watanabe, Makiko Meguro-Horike, Yuta Imai, Yuki Hiroshima, Shin-Ichi Horike, Koichi Kokame, Eriko Morishita. First report of inherited protein S deficiency caused by paternal PROS1 mosaicism. Haematologica. 2021. 107. 1. 330-333
  • Makoto Osada, Keiko Maruyama, Koichi Kokame, Ryunosuke Denda, Kohei Yamazaki, Hisako Kunieda, Maki Hirao, Seiji Madoiwa, Nobuo Okumura, Mitsuru Murata, et al. A novel homozygous variant of the thrombomodulin gene causes a hereditary bleeding disorder. Blood Advances. 2021
  • Keiko Maruyama, Koichi Kokame. Carrier frequencies of antithrombin, protein C, and protein S deficiency variants estimated using a public database and expression experiments. Research and Practice in Thrombosis and Haemostasis. 2021. 5. 1. 179-186
  • Miyu Usui, Tadashi Ozawa, Younhee Kim, Takafumi Mashiko, Kosuke Matsuzono, Keiko Maruyama, Koichi Kokame, Rie Usui, Reiji Koide, Shigeru Fujimoto. Cerebral venous sinus thrombosis associated with protein S deficiency during pregnancy: a case report. Journal of Obstetrics and Gynaecology. 2020. 40. 1. 135-136
ｍore...
MISC (3)：
  • Keiko MARUYAMA, Koichi KOKAME. Estimating the frequencies of pathogenic variants of antithrombin, protein C, and protein S using a public database and expression experiments. Japanese Journal of Thrombosis and Hemostasis. 2021. 32. 5. 635-637
  • Keiko MARUYAMA. ELISA-based detection system for Protein S K196E mutation, a genetic risk factor for venous thromboembolism. Japanese Journal of Thrombosis and Hemostasis. 2016. 27. 4. 466-470
  • 宮田敏行, 丸山慶子. 日本人における先天性血栓性素因-欧米との比較-. 臨床血液. 2014. 55. 8. 908-916
Books (3)：
  • 臨床に直結する血栓止血学 改訂2版
    中外医学社 2018 ISBN:9784498125797
  • 動脈・静脈の疾患(上)
    日本臨牀社 2017
  • 止血・血栓ハンドブック
    西村書店 2015
Education (3)：
  • 2010 - 2013 金沢大学大学院 医学系研究科 博士後期課程(保健学専攻)
  • 2008 - 2010 Kanazawa University
  • 2004 - 2008 Kanazawa University
Work history (5)：
  • 2023/12 - 現在 国立研究開発法人国立循環器病研究センター 研究所 分子病態部 上級研究員
  • 2020/04 - 2023/11 National Cerebral and Cardiovascular Center, Research Institute Department of Molecular Pathogenesis
  • 2017/04 - 2020/03 National Cerebral and Cardiovascular Center, Research Institute Department of Molecular Pathogenesis
  • 2016/04 - 2017/03 National Cerebral and Cardiovascular Center, Research Institute Department of Molecular Pathogenesis
  • 2013/04 - 2016/03 National Cerebral and Cardiovascular Center, Research Institute Department of Molecular Pathogenesis
Awards (2)：
  • 2022/06 - 日本血栓止血学会 第44回日本血栓止血学会学術集会 優秀ポスター賞
  • 2016/06 - 日本血栓止血学会 第21回日本血栓止血学会学術奨励賞
Association Membership(s) (3)：
日本検査血液学会 ,  日本血液学会 ,  日本血栓止血学会
※ Researcher’s information displayed in J-GLOBAL is based on the information registered in researchmap. For details, see here.

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