Sayuki Hirano, Yohei Kondo, Noriyuki Kinoshita, Tetsuhisa Otani, Mikio Furuse, Naoto Ueno, Kazuhiro Aoki. ZO-1 shuttles between tight junctions and podosomes by riding ERK activation waves during collective cell migration. bioRxiv. 2024
Sayuki Hirano, Yusuke Mii, Guillaume Charras, Tatsuo Michiue. Alignment of the cell long axis by unidirectional tension acts cooperatively with Wnt signalling to establish planar cell polarity. Development. 2022. 149. 12
Sayuki Hirano, Takayoshi Yamamoto, Tatsuo Michiue. FRET-based tension measurement across actin-associated mechanotransductive structures using Lima1. The International Journal of Developmental Biology. 2018. 62. 9-10. 631-636
Dynamic redistribution of adhesion-related molecules tunes collective cell behavior
(International Symposium - Physical Biology of Multicellular Dynamics 2026)
Spatiotemporal dynamics of ZO-1 localization in epithelial cell collectives
(Singapore-Japan Mini-workshop on Coordination and Competition in Multicellular Systems 2025)
ERK-dependent translocation of ZO-1 regulates epithelial cell invasion
(The 84th Annual Meeting of the Japanese Cancer Association 2025)
ERK-Driven Relocation of ZO-1 to Podosomes during Collective Cell Migration
(Winter Q-Bio Conference 2025 2025)
ZO-1 shuttles between tight junctions and podosomes riding on ERK activation waves and facilitates cell invasion
(The 47th Annual Meeting of the Molecular Biology Society of Japan 2024)
2019 - 2022 The University of Tokyo Graduate School of Arts and Sciences Multi-Disciplinary Sciences Life Sciences, Doctor's course
2017 - 2019 The University of Tokyo Graduate School of Arts and Sciences Multi-Disciplinary Sciences Life Sciences, Master's course
2012 - 2017 The University of Tokyo College of Arts and Sciences Integrated Sciences
Professional career (1)：
Doctor of Philosophy (The University of Tokyo)
Work history (6)：
2025/03 - 現在 Kyoto University Graduate School of Biostudies Assistant Professor
2024/04 - 2025/02 Kyoto University Graduate School of Biostudies Program-Specific Researcher (JSPS-PD)
2023/04 - 2024/03 National Institutes of Natural Sciences Exploratory Research Center on Life and Living Systems (ExCELLS) JSPS Postdoctoral Fellow
2022/04 - 2023/03 National Institute for Basic Biology Spectrography and Bioimaging Facility Project Research Stuff
2019/04 - 2022/03 Japan Society for the Promotion of Science Research Fellow (DC1)
2020/01 - 2020/09 Japan Society for the Promotion of Science JSPS-ERC Research Fellow
Show all
Awards (3)：
2024/10 - The Naito Foundation Poster Award for Excellence in The 52nd Naito Conference ERK-driven translocation of ZO1 to cell-ECM adhesion structure exerts traction force for promoting collective cell migration and invasion
2023/06 - Tight Junction Symposium 2023 The Best Selected Talk Award Subcellular Shuttling of ZO-1 Facilitates Collective Cell Migration
2019/03 - The University of Tokyo Outstanding Graduate Student Award
Association Membership(s) (4)：
Japan Society for Cell Biology
, Japanese Society of Developmental Biologists
, The Molecular Biology Society of Japan
, The Zoological Society of Japan
