Rchr
J-GLOBAL ID:202101015376394256   Update date: Jun. 24, 2024

Hiratsuka Toru

ヒラツカ トオル | Hiratsuka Toru
Affiliation and department:
Job title: Researcher
Other affiliations (2):
Research field  (3): Tumor biology ,  Dermatology ,  Cell biology
Research keywords  (5): Intercellular signal transduction ,  stem cells ,  Dermatology ,  ERK MAPK ,  in vivo live imaging
Research theme for competitive and other funds  (3):
  • 2024 - 2027 受容体型チロシンキナーゼHERの新規活性抑制機構に基づく創薬とがん治療応用
  • 2022 - 2024 膵癌におけるERKシグナルの揺らぎの観察と制御
  • 2021 - 2023 発癌過程におけるERKシグナルダイナミクスの腫瘍横断的検討
Papers (15):
  • Emanuel Rognoni, Georgina Goss, Toru Hiratsuka, Kalle H Sipilä, Thomas Kirk, Katharina I Kober, Prudence PokWai Lui, Victoria Sk Tsang, Nathan J Hawkshaw, Suzanne M Pilkington, et al. Role of distinct fibroblast lineages and immune cells in dermal repair following UV radiation-induced tissue damage. eLife. 2021. 10
  • Toru Hiratsuka, Ignacio Bordeu, Gunnar Pruessner, Fiona M. Watt. Regulation of ERK basal and pulsatile activity control proliferation and exit from the stem cell compartment in mammalian epidermis. Proceedings of the National Academy of Sciences. 2020. 117. 30. 17796-17807
  • Simon Brayford, Fiona N Kenny, Toru Hiratsuka, Eduardo Serna-Morales, Lawrence Yolland, Andrei Luchici, Brian M Stramer. Heterotypic contact inhibition of locomotion can drive cell sorting between epithelial and mesenchymal cell populations. Journal of cell science. 2019. 132. 11
  • Toru Hiratsuka, Naoki Komatsu. Single-Cell Live Imaging. Methods in molecular biology (Clifton, N.J.). 2019. 1979. 409-421
  • Emanuel Rognoni, Angela Oliveira Pisco, Toru Hiratsuka, Kalle H Sipilä, Julio M Belmonte, Seyedeh Atefeh Mobasseri, Christina Philippeos, Rui Dilão, Fiona M Watt. Fibroblast state switching orchestrates dermal maturation and wound healing. Molecular systems biology. 2018. 14. 8. e8174
more...
MISC (3):
  • 青木 一洋, 平塚 徹, 松田 道行. Intercellular propagation of ERK MAP kinase signal transduction. 生体の科学. 2016. 67. 2. 132-136
  • Toru Hiratsuka, Shinsuke Matsuzaki, Shingo Miyata, Mitsuhiro Kinoshita, Kazuaki Kakehi, Taiichi Katayama, Masaya Tohyama. Inhibitory effect of Ferulic acid against ER stress could suggest the clinical validity of Yokukansan, a Japanese herbal medicine. NEUROSCIENCE RESEARCH. 2010. 68. E190-E190
  • Toru Hiratsuka, Shinsuke Matsuzaki, Shingo Miyata, Taiichi Katayama, Masaya Tohyama. Rhizoma (Senkyu), one of various components of Yokukansan reduced the ER stress induced cell toxicity resulting in the good effect on the Alzheimer disease associated cell death. NEUROSCIENCE RESEARCH. 2009. 65. S245-S245
Books (1):
  • Single-Cell Live Imaging (chapter in Methods in molecular biology (Clifton,N.J.) )
    2019 ISBN:9781493992393
Lectures and oral presentations  (3):
  • ERK MAPK pulses control exit from the stem cell compartment in mammalian epidermis
    (Gordon Research Conference, Epithelial Differentiation and Keratinization 2019)
  • The role of pulsing activity of ERK MAPK in keratinocyte differentiation
    (London Skin Club 2018)
  • Spatial and temporal dynamics of ERK MAPK in mouse epidermis and human keratinocytes.
    (Cold Spring Harbor meeting: Stem Cell Biology 2017)
Education (2):
  • 2011 - 2015 Kyoto University Graduate School of Medicine Graduate School of Medicine
  • 2005 - 2011 Osaka University Faculty of Medicine Medical School
Work history (3):
  • 2022/01 - 現在 Osaka International Cancer Institute Department of Oncology and Growth Regulation Researcher
  • 2021/04 - 2022/12 Kyoto University Graduate School of Biostudies Program-Specific Assistant Professor
  • 2015/06 - 2021/03 King's College London Centre for Stem Cells and Regenerative Medicine Research Associate
Awards (4):
  • 2015/03 - Outstanding Oral Presentation in Long Talk Session, The 13th International Student Seminar, Kyoto, Japan
  • 2014/05 - EMBO Conference Cellular signalling and cancer therapy, EACR Poster Prize
  • 2011/03 - 大阪大学 山村賞
  • 2010/12 - 日本学生支援機構 優秀学生顕彰 優秀賞
Association Membership(s) (4):
日本分子生物学会 ,  日本細胞生物学会 ,  日本生化学会 ,  日本癌学会
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