Rchr
J-GLOBAL ID：202101018981792351
Update date: Aug. 07, 2024
Ogasawara Sadahisa
オガサワラ サダヒサ | Ogasawara Sadahisa
Affiliation and department：
Job title：
Assistant Professor
Research field (1)：
Gastroenterology
Research keywords (7)：
肝動注療法(HAIC)
, 肝動脈化学塞栓術(TACE)
, 免疫療法
, 分子標的薬治療
, Clinical Trial
, Hepatology
, Hepatocellular Carcinoma
Research theme for competitive and other funds (8)：
- 2024 - 2027 Deciphering haptic glucose regulatory mechanism through liver FoxO1 PPARA in liver-fat axis and its clinical application
- 2023 - 2026 Development of all-round combination immunotherapy for advanced liver cancer
- 2019 - 2025 Single arm study to evaluate the safety and efficacy of ramucirumab in advanced hepatocellular carcinoma patients in Japanese real-world practice; focusing on the completion of the REACH-2 study
- 2022 - 2025 Analysis of tumor antigen recognition of T cell accumulated in the underlying liver of hepatocellular carcinoma
- 2020 - 2024 A phase Ib study of durvalumab (MEDI4736) tremelimumab combined with particle therapy in advanced hepatocellular carcinoma patients with macrovascular invasion
- 2022 - 2023 地域医療機関において診療に難渋する症例に対する医師間オンライン コンサルテーションシステムの構築
- 2021 - 2023 Understandings the mechanism of energy metabolization in intratumor immune microenvironment in metabolic related hepatocellular carcinoma
- 2021 - 2022 進行肝細胞癌に対する革新的治療開発を目指した重粒子線治療 と免疫チェックポイント阻害薬の併用療法の免疫応答機構の解明
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Papers (127)：
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Hidehiro Kamezaki, Terunao Iwanaga, Takahiro Maeda, Junichi Senoo, Sadahisa Ogasawara, Naoya Kato. A Comparison of the Effects of Alcohol Abstinence and Drinking Habit on the Survival of Patients with Alcohol-related Cirrhosis: A Retrospective Observational Study. Internal medicine (Tokyo, Japan). 2024
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Tomomi Ozaki, Sae Yumita, Sadahisa Ogasawara, Makoto Fujiya, Takahiro Tsuchiya, Ryohei Yoshino, Midori Sawada, Teppei Akatsuka, Ryo Izai, Chihiro Miwa, et al. Cytokine release syndrome following durvalumab and tremelimumab in advanced hepatocellular carcinoma: A case report with cytokine and damage-associated molecular pattern analysis. Hepatology research : the official journal of the Japan Society of Hepatology. 2024
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Kazufumi Kobayashi, Sadahisa Ogasawara, Ei Itobayashi, Tomomi Okubo, Norio Itokawa, Kazuyoshi Nakamura, Michihisa Moriguchi, Shunji Watanabe, Masafumi Ikeda, Hidekatsu Kuroda, et al. Ramucirumab for advanced hepatocellular carcinoma in the current real world: a Japanese single-arm study post-REACH-2 (The R-evolution study). Investigational new drugs. 2024
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Yukie Tahara, Ayumi Amemiya, Ryutaro Kase, Yuka Kitagawa, Sadahisa Ogasawara, Naoya Kato, Masatoshi Komiyama. Relationship between hand-foot skin reaction and external force on patients with hepatocellular carcinoma: A cohort study. European Journal of Oncology Nursing. 2024. 70. 102576-102576
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Masanori Inoue, Sadahisa Ogasawara, Kazufumi Kobayashi, Tomomi Okubo, Norio Itokawa, Masamichi Obu, Kentaro Fujimoto, Hidemi Unozawa, Sae Yumita, Kisako Fujiwara, et al. Assessment of Macrovascular Invasion in Advanced Hepatocellular Carcinoma: Clinical Implications and Treatment Outcomes with Systemic Therapy. Liver Cancer. 2024
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MISC (382)：
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井上将法, 興梠慧輔, 小林和史, 叶川直哉, 小笠原定久, 加藤直也. Changes and Future Perspectives in Sequential Therapy for Hepatocellular Carcinoma. 臨床消化器内科. 2024. 39. 5
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神崎洋彰, 小笠原定久, 加藤直也. 肝細胞癌の進化と腫瘍微小環境の変遷. 日本消化器病学会雑誌(Web). 2024. 121
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米本卓弥, 小笠原定久, 井上将法, 小林和史, 叶川直哉, 清野宗一郎, 中村昌人, 近藤孝行, 中本晋吾, 加藤直也. 進行肝細胞癌に対するSTRIDE療法における臨床的課題の検証;2パターンの免疫療法再投与の意義. 日本消化器病学会雑誌(Web). 2024. 121
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叶川直哉, 小笠原定久, 後藤千尋, 堀尾亮輔, 大内麻愉, 菅元泰, 興梠慧輔, 對田尚, 加藤順, 加藤直也. Establishment of an online consultation system among physicians for cases that are difficult to treat at local medical institutions. 日本遠隔医療学会雑誌. 2024. 19
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藤本健太郎, 近藤孝行, 近藤孝行, 宇野澤秀美, 藤原希彩子, 小林和史, 清野宗一郎, 叶川直哉, 小笠原定久, 中本晋吾, et al. 門脈圧亢進症における脾硬度測定の有用性~脂肪肝の及ぼす影響を踏まえて~. 日本消化器病学会雑誌(Web). 2024. 121
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Lectures and oral presentations (2)：
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How Can We Boost T Cell Responses during Immune Checkpoint Inhibitor Therapy in Hepatocellular Carcinoma?
(The Liver Week 2023 2023)
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最新の肝細胞癌治療戦略
(JCRミッドサマーセミナー 2022)
Education (2)：
- 2008 - 2012 Chiba University Graduate School of Medicine
- 1998 - 2004 Chiba University School of Medicine
Professional career (2)：
- M.D (Chiba University)
- Ph.D (Chiba University)
Work history (6)：
Awards (3)：
- 2022/03 - Gilead Sience Gilead’s Research Scholars Program Liver Disease Awards
- 2019/11 - JDDW 2019 若手奨励賞
- 2018/10 - JDDW 2018 The Best Presenter Award in International Session
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