Rchr
J-GLOBAL ID:202101020668500913   Update date: Feb. 01, 2024

Nishi Kiyoto

ニシ キヨト | Nishi Kiyoto
Affiliation and department:
Job title: Assistant professor
Research field  (3): Pathobiochemistry ,  Metabolism and endocrinology ,  Pharmacology
Research theme for competitive and other funds  (9):
  • 2023 - 2026 多機能ペプチダーゼによる新規エネルギー代謝制御機構の解明と治療応用への展開
  • 2023 - 2024 新規栄養センサー分子による熱産生制御機構の解明と治療応用への展開
  • 2021 - 2023 アミノ酸代謝産物によるピルビン酸代謝制御機構の解明
  • 2017 - 2018 心疾患におけるエネルギー代謝の多面的作用の解明
  • 2017 - 2018 エネルギー代謝における新規臓器連関の解明
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Papers (24):
  • Satsuki Takashima, Eiichi Okamura, Yusuke Ichiyama, Kiyoto Nishi, Akio Shimizu, Chisato Watanabe, Masanaga Muto, Shoma Matsumoto, Setsuko Tsukiyama-Fujii, Tomoyuki Tsukiyama, et al. Null mutation of exocyst complex component 3-like does not affect vascular development in mice. Experimental animals. 2023
  • Kiyoto Nishi, Akira Yoshii, Lauren Abell, Bo Zhou, Ricardo Frausto, Julia Ritterhoff, Timothy S McMillen, Ian Sweet, Yibin Wang, Chen Gao, et al. Branched-chain keto acids inhibit mitochondrial pyruvate carrier and suppress gluconeogenesis in hepatocytes. Cell reports. 2023. 42. 6. 112641-112641
  • Sayaka Saijo, Mikiko Ohno, Hirotaka Iwasaki, Shintaro Matsuda, Kiyoto Nishi, Yoshinori Hiraoka, Natsuki Ide, Takeshi Kimura, Eiichiro Nishi. Nardilysin in adipocytes regulates UCP1 expression and body temperature homeostasis. Scientific reports. 2022. 12. 1. 3449-3449
  • Kimihiro Nishimura, Yukihiro Fujita, Shogo Ida, Tsuyoshi Yanagimachi, Natsuko Ohashi, Kiyoto Nishi, Atsushi Nishida, Yasumasa Iwasaki, Katsutaro Morino, Satoshi Ugi, et al. Glycaemia and body weight are regulated by sodium-glucose cotransporter 1 (SGLT1) expression via O-GlcNAcylation in the intestine. Molecular metabolism. 2022. 59. 101458-101458
  • Daisuke Yasuda, Yoshinori Hiraoka, Mikiko Ohno, Kiyoto Nishi, Hirotaka Iwasaki, Toru Kita, Eiichiro Nishi, Noriaki Kume. Deficiency of Nardilysin in the Liver Reduces Serum Cholesterol Levels. Biological & pharmaceutical bulletin. 2021. 44. 3. 363-371
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MISC (52):
  • Ohno Mikiko, Nishi Kiyoto, Matsuura Hiroshi, Makiyama Takeru, Koujitani Hirohiko, Matsuda Shintaro, Kimura Takeshi, Nishi Eiichiro. Metalloprotease Nardilysin regulates sinus automaticity through transcriptional regulation of ion channels. Proceedings for Annual Meeting of The Japanese Pharmacological Society. 2022. 95. 3-O-110
  • 大野美紀子, 西清人, 大林徹也, 西英一郎. ナルディライジン酵素活性の生体内における意義. 日本病態プロテアーゼ学会学術集会プログラム抄録集. 2022. 27th
  • 西清人, 岩崎広高, 大野美紀子, 西英一郎. 肝細胞のナルディライジンは褐色脂肪組織の熱産生を制御する. 日本病態プロテアーゼ学会学術集会プログラム抄録集. 2022. 27th
  • Nishi Kiyoto, Abell Lauren, Frausto Ricardo, Ritterhoff Julia, McMillen Timothy, Sweet Ian, Wang Yibin, Gao Chen, Tian Rong. Branched-Chain Keto Acid Inhibits Mitochondrial Pyruvate Carrier and Suppresses Gluconeogenesis. Cell Press Sneak Peek. 2022
  • 大野美紀子, 松浦博, 牧山武, 糀谷泰彦, 西清人, 松田真太郎, 木村剛, 西英一郎. NRDC regulates sinus automaticity through transcriptional regulation of ionchannels. 日本循環薬理学会口演要旨集. 2021. 31st
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Education (2):
  • 2010 - 2014 Kyoto University Graduate School of Medicine
  • 1999 - 2005 Kyoto University Faculty of Medicine
Professional career (1):
  • M.D. Ph.D. (Kyoto University)
Work history (6):
  • 2021/04 - 現在 Shiga University of Medical Science Department of Pharmacology Assistant Professor
  • 2017/06 - 2021/03 University of Washington Mitochondria and Metabolism Center Senior Fellow
  • 2016/04 - 2017/06 Kyoto University Hospital Clinical fellow
  • 2014/04 - 2016/03 Kyoto University Hospital Resercher
  • 2007/04 - 2010/03 兵庫県立尼崎病院 循環器内科 後期研修医
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Awards (7):
  • 2022/12 - 第96回 日本薬理学会年会 優秀発表賞(YIA)
  • 2021/12 - 第38回 滋賀医科大学シンポジウム 優秀賞
  • 2016/08 - 日本肥満学会 アディポサイエンスシンポジウム 若手優秀研究奨励賞
  • 2014/05 - 日本生化学会 近畿支部例会 優秀発表賞
  • 2013/05 - 公益財団法人 興和生命科学振興財団 国際交流助成
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