Art

J-GLOBAL ID：202102210703377619   Reference number：21A0830562

Transcriptional Regulation of Wnt/β-Catenin Pathway in Colorectal Cancer

大腸癌におけるWnt/β-カテニン経路の転写調節【JST・京大機械翻訳】

Author (8)： Bian Jia (Centre for Cancer Research, Hudson Institute of Medical Research, Clayton, VIC 3168, Australia) ,  Bian Jia (Department of Molecular and Translational Science, Monash University, Clayton, VIC 3800, Australia) ,  Dannappel Marius (Centre for Cancer Research, Hudson Institute of Medical Research, Clayton, VIC 3168, Australia) ,  Dannappel Marius (Department of Molecular and Translational Science, Monash University, Clayton, VIC 3800, Australia) ,  Wan Chunhua (Centre for Cancer Research, Hudson Institute of Medical Research, Clayton, VIC 3168, Australia) ,  Wan Chunhua (Department of Molecular and Translational Science, Monash University, Clayton, VIC 3800, Australia) ,  Firestein Ron (Centre for Cancer Research, Hudson Institute of Medical Research, Clayton, VIC 3168, Australia) ,  Firestein Ron (Department of Molecular and Translational Science, Monash University, Clayton, VIC 3800, Australia)
Material： Cells (Web)
Volume： 9  Issue： 9  Page： 2125  Publication year： 2020 
JST Material Number： U7155A  ISSN： 2073-4409  Document type： Article
Article type： 文献レビュー  Country of issue： Switzerland (CHE)  Language： ENGLISH (EN)

Abstract/Point： The Wnt/-catenin signaling pat...

Register(free) or Log In to access     To see more with JDream III (charged).   {{ this.onShowAbsJLink("http://jdream3.com/lp/jglobal/index.html?docNo=21A0830562&from=J-GLOBAL&jstjournalNo=U7155A") }}

Thesaurus term： chromatin ,  embryogenesis ,  carcinogenicity ,  homeostasis ,  adult(development) ,  *colorectal neoplasm ,  *catenin ,  epigenetics
Semi thesaurus term： Wntシグナル ,  *Wnt蛋白質 ,  *βカテニン ,  転写活性 ,  *転写調節 ,  標的遺伝子 ,  結腸直腸癌 , 【Automatic Indexing@JST】

Author keywords (4)： Wnt/β-catenin signaling pathway ,  transcriptional regulation ,  epigenetic regulation ,  colorectal cancer

JST classification (1)： Cell physiology in general  (EF02010S)

Reference (256)：

• Huber, A.H.; Nelson, W.J.; Weis, W.I. Three-dimensional structure of the armadillo repeat region of beta-catenin. Cell 1997, 90, 871-882.
• Liu, C.; Li, Y.; Semenov, M.; Han, C.; Baeg, G.H.; Tan, Y.; Zhang, Z.; Lin, X.; He, X. Control of beta-catenin phosphorylation/degradation by a dual-kinase mechanism. Cell 2002, 108, 837-847.
• Aberle, H.; Bauer, A.; Stappert, J.; Kispert, A.; Kemler, R. β-catenin is a target for the ubiquitin-proteasome pathway. EMBO J. 1997, 16, 3797-3804.
• Hart, M.; Concordet, J.P.; Lassot, I.; Albert, I.; del los Santos, R.; Durand, H.; Perret, C.; Rubinfeld, B.; Margottin, F.; Benarous, R.; et al. The F-box protein beta-TrCP associates with phosphorylated beta-catenin and regulates its activity in the cell. Curr. Biol. 1999, 9, 207-210.
• Wu, G.; Huang, H.; Garcia Abreu, J.; He, X. Inhibition of GSK3 phosphorylation of beta-catenin via phosphorylated PPPSPXS motifs of Wnt coreceptor LRP6. PLoS ONE 2009, 4, e4926.

Terms in the title (5)： 大腸癌 ,  Wnt ,  β-カテニン ,  経路 ,  転写調節