Art

J-GLOBAL ID：202102212909242328   Reference number：21A0132574

Nucleation Kinetics Estimated by Using the Modified Induction Time in Cooling Crystallization and the Applicability to the Combined Process of Antisolvent and Cooling Crystallization

冷却結晶化における修正誘導時間を用いて推定した核形成速度論と反溶媒と冷却結晶化の組合せプロセスへの適用性

Author (4)： Kodera Takanori (API Research Japan, Pharmaceutical Science and Technology Core Function Unit, Eisai Co., Ltd.) ,  Kobari Masanori (EN Technology Center, JGC Corporation) ,  Kobari Masanori (Major in Applied Chemistry, Graduate School of Advanced Science and Engineering, Waseda University) ,  Hirasawa Izumi (Major in Applied Chemistry, Graduate School of Advanced Science and Engineering, Waseda University)
Material： Journal of Chemical Engineering of Japan  (J Chem Eng Jpn)
Volume： 53  Issue： 11  Page： 698-707(J-STAGE)  Publication year： 2020 
JST Material Number： S0629A  ISSN： 0021-9592  CODEN： JCEJAQ  Document type： Article
Article type： 原著論文  Country of issue： Japan (JPN)  Language： ENGLISH (EN)

Thesaurus term： *crystallization ,...
Semi thesaurus term： *drug medicine ,...

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Author keywords (10)： Primary Nucleation Kinetics ,  Modified Induction Time ,  Cooling Crystallization ,  Combined Crystallization ,  Pharmaceutical Industry ,  Primary Nucleation Kinetics ,  Modified Induction Time ,  Cooling Crystallization ,  Combined Crystallization ,  Pharmaceutical Industry

JST classification (2)： Crystal growth in general  (BK13010Q) ,  Production in general  (GU01051P)

Reference (16)：

• Chen, J., B. Sarma, J. M. B. Evans and A. S. Myerson; “Pharmaceutical Crystallization,” Cryst. Growth Des., 11, 887-895 (2011)
• Hojjati, H. and S. Rohani; “Measurement and Prediction of Solubility of Paracetamol in Water-Isopropanol Solution. Part 1. Measurement and Data Analysis,” Org. Process Res. Dev., 10, 1101-1109 (2006)
• Knox, M., M. Trifkovic and S. Rohani; “Combining Anti-Solvent and Cooling Crystallization: Effect of Solvent Composition on Yield and Meta Stable Zone Width,” Chem. Eng. Sci., 64, 3555-3563 (2009)
• Kobari, M., N. Kubota and I. Hirasawa; “Computer Simulation of Metastable Zone Width for Unseeded Potassium Sulfate Aqueous Solution,” J. Cryst. Growth, 317, 64-69 (2011)
• Kodera, T., M. Kobari and I. Hirasawa; “Modeling and Growth Kinetics of Antisolvent Crystallization Applied to the Pharmaceutical Industry,” Chem. Eng. Technol., 42, 1458-1465 (2019a)

Terms in the title (7)： 結晶化 ,  誘導時間 ,  推定 ,  核形成速度 ,  反溶媒 ,  組合せプロセス ,  適用性