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J-GLOBAL ID:202102215328425988   Reference number:21A0777996

JAK-STAT Signaling: A Double-Edged Sword of Immune Regulation and Cancer Progression

JAK-STATシグナリング:免疫調節と癌進行の両端剣【JST・京大機械翻訳】
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Material:
Volume: 11  Issue: 12  Page: 2002  Publication year: 2019 
JST Material Number: U7153A  ISSN: 2072-6694  Document type: Article
Article type: 文献レビュー  Country of issue: Switzerland (CHE)  Language: ENGLISH (EN)
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Janus kinase-signal transducer...
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Cell physiology in general 
Reference (235):
  • Thomas, S.J.; Snowden, J.A.; Zeidler, M.P.; Danson, S.J. The role of JAK/STAT signalling in the pathogenesis, prognosis and treatment of solid tumours. Br. J. Cancer 2015, 113, 365-371.
  • Villarino, A.V.; Kanno, Y.; O’Shea, J.J. Mechanisms and consequences of Jak-STAT signaling in the immune system. Nat. Immunol. 2017, 18, 374-384.
  • Groner, B.; von Manstein, V. Jak Stat signaling and cancer: Opportunities, benefits and side effects of targeted inhibition. Mol. Cell. Endocrinol. 2017, 451, 1-14.
  • Jones, L.M.; Broz, M.L.; Ranger, J.J.; Ozcelik, J.; Ahn, R.; Zuo, D.; Ursini-Siegel, J.; Hallett, M.T.; Krummel, M.; Muller, W.J. STAT3 Establishes an Immunosuppressive Microenvironment during the Early Stages of Breast Carcinogenesis to Promote Tumor Growth and Metastasis. Cancer Res. 2016, 76, 1416-1428.
  • Fuertes, M.B.; Kacha, A.K.; Kline, J.; Woo, S.-R.; Kranz, D.M.; Murphy, K.M.; Gajewski, T.F. Host type I IFN signals are required for antitumor CD8+ T cell responses through CD8α+ dendritic cells. J. Exp. Med. 2011, 208, 2005-2016.
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