Art

J-GLOBAL ID：202102215845496370   Reference number：21A0219781

Proteasome phase separation for degradation

ストレスとユビキチンに依存したプロテアソームの液-液相分離

Author (3)： SAEKI YASUSHI (東京都医学総合研) ,  YASUDA SAYAKA (東京都医学総合研) ,  TSUCHIYA HIKARU (東京都医学総合研)
Material： 生化学
Volume： 92  Issue： 6  Page： 822-826  Publication year： Dec. 25, 2020 
JST Material Number： G0184A  ISSN： 0037-1017  CODEN： SEIKAQ  Document type： Article
Article type： 文献レビュー  Country of issue： Japan (JPN)  Language： JAPANESE (JA)

Thesaurus term： *stress (physiology) ,...
Semi thesaurus term： RAD23B ,...

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JST classification (2)： Function of cell components  (EF03060C) ,  Biological function  (EB03040U)

Substance index (1)： Bortezomib

Reference (18)：

• Livneh, I., Cohen-Kaplan, V., Cohen-Rosenzweig, C., Avni, N., & Ciechanover, A. (2016) The life cycle of the 26S proteasome: From birth, through regulation and function, and onto its death. Cell Res., 26, 869-885.
• Pack, C.G., Yukii, H., Toh-e, A., Kudo, T., Tsuchiya, H., Kaiho, A., Sakata, E., Murata, S., Yokosawa, H., Sako, Y., et al. (2014) Quantitative live-cell imaging reveals spatio-temporal dynamics and cytoplasmic assembly of the 26S proteasome. Nat. Commun., 5, 3396.
• Enam, C., Geffen, Y., Ravid, T., & Gardner, R.G. (2018) Protein Quality Control Degradation in the Nucleus. Annu. Rev. Biochem., 87, 725-749.
• Venegas, A.B., Natsume, T., Kanemaki, M., & Hickson, I.D. (2020) Inducible degradation of the human SMC5/6 complex reveals an essential role only during interphase. Cell Rep., 31, 107533.
• Zhang, X., Crowley, V.M., Wucherpfennig, T.G., Dix, M.M., & Cravatt, B.F. (2019) Electrophilic PROTACs that degrade nuclear proteins by engaging DCAF16. Nat. Chem. Biol., 15, 737-746.

Terms in the title (4)： ストレス ,  ユビキチン ,  プロテアソーム ,  液-液相分離