Art

J-GLOBAL ID：202102218136332493   Reference number：21A1902669

A Decreased Level of Soluble Klotho Can Predict Cardiovascular Death in No or Mild Abdominal Aortic Calcification Hemodialysis Patients

可溶性Klothoのレベル低下は,非または軽度の腹部大動脈石灰化血液透析患者における心血管死を予測できる【JST・京大機械翻訳】

Author (10)： Cai Hong (Department of Nephrology, School of Medicine, Renji Hospital, Shanghai Jiao Tong University, Shanghai, China) ,  Zhu Xuying (Department of Nephrology, School of Medicine, Renji Hospital, Shanghai Jiao Tong University, Shanghai, China) ,  Lu Jiayue (Department of Nephrology, School of Medicine, Renji Hospital, Shanghai Jiao Tong University, Shanghai, China) ,  Zhu Minxia (Department of Nephrology, School of Medicine, Renji Hospital, Shanghai Jiao Tong University, Shanghai, China) ,  Liu Shang (Department of Nephrology, School of Medicine, Renji Hospital, Shanghai Jiao Tong University, Shanghai, China) ,  Zhan Yaping (Department of Nephrology, School of Medicine, Renji Hospital, Shanghai Jiao Tong University, Shanghai, China) ,  Ni Zhaohui (Department of Nephrology, School of Medicine, Renji Hospital, Shanghai Jiao Tong University, Shanghai, China) ,  Gu Leyi (Department of Nephrology, School of Medicine, Renji Hospital, Shanghai Jiao Tong University, Shanghai, China) ,  Zhang Weiming (Department of Nephrology, School of Medicine, Renji Hospital, Shanghai Jiao Tong University, Shanghai, China) ,  Mou Shan (Department of Nephrology, School of Medicine, Renji Hospital, Shanghai Jiao Tong University, Shanghai, China)
Material： Frontiers in Medicine (Web)
Volume： 8  Page： 672000  Publication year： 2021 
JST Material Number： U7079A  ISSN： 2296-858X  Document type： Article
Article type： 原著論文  Country of issue： Switzerland (CHE)  Language： ENGLISH (EN)

Abstract/Point： Background: Soluble Klotho pla...

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Thesaurus term： regression analysis ,  serum ,  *death ,  mortality ,  *calcification ,  cardiovascular disease ,  ELISA ,  cause of death ,  chronic kidney disease
Semi thesaurus term： ROC曲線 ,  維持透析 ,  *血液透析患者 ,  予測因子 ,  *大動脈石灰化 ,  総死亡率 , 【Automatic Indexing@JST】

Author keywords (5)： soluble Klotho ,  cardiovascular disease ,  death rate ,  abdominal aorta calcification ,  maintenance hemodialysis

JST classification (3)： Other therapies for urogenital diseases  (GM05040R) ,  Urogenital diseases  (GM03000L) ,  Cardiovascular system diseases  (GJ03000C)

Reference (28)：

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• Hou YC, Lu CL, Lu KC. Mineral bone disorders in chronic kidney disease. Nephrology. (2018) 23(Suppl.):88-94. doi: 10.1111/nep.13457
• Kuro-o M. The Klotho proteins in health and disease. Nat Rev Nephrol. (2019) 15:27-44. doi: 10.1038/s41581-018-0078-3
• Barker SL, Pastor J, Carranza D, Quinones H, Griffith C, Goetz R, et al. The demonstration of alphaklotho deficiency in human chronic kidney disease with a novel synthetic antibody. Nephrol Dial Transplant. (2015) 30:223-33. doi: 10.1093/ndt/gfu291
• Xie J, Yoon SW, An SW, Kuro-o M, Huang CL. Soluble klotho protects against uremic cardiomyopathy independently of broblast growth factor 23 and phosphate. J Am Soc Nephrol. (2015) 26:1150-60. doi: 10.1681/ASN.2014040325

Terms in the title (6)： 可溶性 ,  軽度 ,  腹部大動脈石灰化 ,  血液透析患者 ,  心血管死 ,  予測