Art

J-GLOBAL ID：202102218906784305   Reference number：21A2329048

Renal Delivery of Pharmacologic Agents During Machine Perfusion to Prevent Ischaemia-Reperfusion Injury: From Murine Model to Clinical Trials

虚血再灌流障害を予防するための機械潅流中の薬理学的薬剤の腎送達:マウスモデルから臨床試験まで【JST・京大機械翻訳】

Author (7)： Franzin Rossana (1Department of Emergency and Organ Transplantation, Nephrology, Dialysis and Transplantation Unit, University of Bari Aldo Moro, Bari, Italy) ,  Stasi Alessandra (1Department of Emergency and Organ Transplantation, Nephrology, Dialysis and Transplantation Unit, University of Bari Aldo Moro, Bari, Italy) ,  Fiorentino Marco (1Department of Emergency and Organ Transplantation, Nephrology, Dialysis and Transplantation Unit, University of Bari Aldo Moro, Bari, Italy) ,  Simone Simona (1Department of Emergency and Organ Transplantation, Nephrology, Dialysis and Transplantation Unit, University of Bari Aldo Moro, Bari, Italy) ,  Oberbauer Rainer (2Department of Nephrology and Dialysis, University Clinic for Internal Medicine III, Medical University Vienna, Vienna, Austria) ,  Castellano Giuseppe (3Nephrology, Dialysis and Transplantation Unit, Advanced Research Center on Kidney Aging (A.R.K.A.), Department of Medical and Surgical Sciences, University of Foggia, Foggia, Italy) ,  Gesualdo Loreto (1Department of Emergency and Organ Transplantation, Nephrology, Dialysis and Transplantation Unit, University of Bari Aldo Moro, Bari, Italy)
Material： Frontiers in Immunology (Web)
Volume： 12  Page： 673562  Publication year： 2021 
JST Material Number： U7074A  ISSN： 1664-3224  Document type： Article
Article type： 文献レビュー  Country of issue： Switzerland (CHE)  Language： ENGLISH (EN)

Abstract/Point： Donor organ shortage still rem...

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Thesaurus term： complement(immunology) ,  antiphlogistic ,  *clinical trial ,  *perfusion ,  *pharmacology ,  kidney transplantation ,  fibrous disease ,  renal insufficiency ,  therapeutic planning ,  oxidative stress ,  siRNA ,  donor
Semi thesaurus term： *再潅流障害 ,  ex vivo実験 ,  *マウスモデル , 【Automatic Indexing@JST】

Author keywords (8)： renal ischemia/reperfusion ,  machine perfusion ,  hypothermic perfusion ,  normothermic perfusion ,  DCD - donation after cardiac death ,  ECD - expanded donor criteria ,  complement system ,  senolytic agents

JST classification (1)： Surgical treatment for urogenital diseases  (GM05030G)

Reference (213)：

• Sacks SH, Zhou W, Pani A, Campbell RD, Martin J. Complement C3 Gene Expression and Regulation in Human Glomerular Epithelial Cells. Immunology (1993) 79:348-54.
• Hernández D, Alonso-Titos J, Armas-Padrón AM, Lopez V, Cabello M, Sola E, et al. Waiting List and Kidney Transplant Vascular Risk: An Ongoing Unmet Concer. Kidney Blood Press Res (2020) 45:1-27. doi: doi: 10.1159/000504546
• Schold J, Srinivas TR, Sehgal AR, Meier-Kriesche H-U. Half of Kidney Transplant Candidates Who are Older Than 60 Years Now Placed on the Waiting List Will Die Before Receiving a Deceased-Donor Transplant. Clin J Am Soc Nephrol (2009) 4:1239-45. doi: doi: 10.2215/CJN.01280209
• Hosgood SA, Hoff M, Nicholson ML. Treatment of Transplant Kidneys During Machine Perfusion. Transpl Int (2021) 34(2):224-32. doi: doi: 10.1111/tri.13751
• Molacek J, Opatrný V, Treska V, Matejka R, Hes O. Options to Improve the Quality of Kidney Grafts From Expanded Criteria Donors Experimental Study. Rozhl Chir (2018) 97:193-201. doi: 10.1111/tri.13751

Terms in the title (9)： 虚血再灌流障害 ,  予防 ,  潅流 ,  薬理学 ,  薬剤 ,  腎 ,  送達 ,  マウスモデル ,  臨床試験