Art

J-GLOBAL ID：202102221088719770   Reference number：21A0188145

Costunolide and dehydrocostuslactone from Saussurea lappa root inhibit autophagy in hepatocellular carcinoma cells

Saussurea lappa根からのコスツノリドとデヒドロコスツスラクトンは肝細胞癌細胞のオートファジーを阻害する

Author (7)： Okubo Shinya (Graduate School of Pharmaceutical Sciences, Nagasaki International University, Sasebo, Nagasaki, Japan) ,  Ohta Tomoe (Faculty of Pharmaceutical Sciences, Nagasaki International University, Sasebo, Nagasaki, Japan) ,  Fujita Hideaki (Graduate School of Pharmaceutical Sciences, Nagasaki International University, Sasebo, Nagasaki, Japan) ,  Fujita Hideaki (Faculty of Pharmaceutical Sciences, Nagasaki International University, Sasebo, Nagasaki, Japan) ,  Shoyama Yukihiro (Faculty of Pharmaceutical Sciences, Nagasaki International University, Sasebo, Nagasaki, Japan) ,  Uto Takuhiro (Graduate School of Pharmaceutical Sciences, Nagasaki International University, Sasebo, Nagasaki, Japan) ,  Uto Takuhiro (Faculty of Pharmaceutical Sciences, Nagasaki International University, Sasebo, Nagasaki, Japan)
Material： Journal of Natural Medicines  (J Nat Med)
Volume： 75  Issue： 1  Page： 240-245  Publication year： 2021 
JST Material Number： L5856A  ISSN： 1340-3443  Document type： Article
Article type： 短報  Country of issue： Germany, Federal Republic of (DEU)  Language： ENGLISH (EN)

Thesaurus term： Compositae ,...
Semi thesaurus term： LC3-II ,...

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Author keywords (5)： Autophagy ,  Saussurea lappa ,  Costunolide ,  Dehydrocostuslactone ,  Hepatocellular carcinoma

JST classification (3)： Basic research of pharmacology of crude drugs  (GX06020J) ,  Basic research of antitumor(=antineoplastic)drugs  (GW16010A) ,  Monoterpenes,sesquiterpenes  (CF10022A)

Substance index (2)： Costunolide ,  Dehydrocostuslactone

Terms in the title (8)： Saussurea ,  根 ,  コスツノリド ,  デヒドロコスツスラクトン ,  肝細胞 ,  癌細胞 ,  オートファジー ,  阻害