Art

J-GLOBAL ID：202102225886658778   Reference number：21A0826950

Dissecting Aging and Senescence-Current Concepts and Open Lessons

老化と老化の精査-現在の概念とオープンな教訓【JST・京大機械翻訳】

Author (9)： Schmeer Christian (Hans-Berger Department of Neurology, Jena University Hospital, 07747 Jena, Thuringia, Germany) ,  Schmeer Christian (Jena Center for Healthy Ageing, Jena University Hospital, 07747 Jena, Thuringia, Germany) ,  Kretz Alexandra (Hans-Berger Department of Neurology, Jena University Hospital, 07747 Jena, Thuringia, Germany) ,  Kretz Alexandra (Jena Center for Healthy Ageing, Jena University Hospital, 07747 Jena, Thuringia, Germany) ,  Wengerodt Diane (Hans-Berger Department of Neurology, Jena University Hospital, 07747 Jena, Thuringia, Germany) ,  Stojiljkovic Milan (Hans-Berger Department of Neurology, Jena University Hospital, 07747 Jena, Thuringia, Germany) ,  Stojiljkovic Milan (Jena Center for Healthy Ageing, Jena University Hospital, 07747 Jena, Thuringia, Germany) ,  Witte Otto W. (Hans-Berger Department of Neurology, Jena University Hospital, 07747 Jena, Thuringia, Germany) ,  Witte Otto W. (Jena Center for Healthy Ageing, Jena University Hospital, 07747 Jena, Thuringia, Germany)
Material： Cells (Web)
Volume： 8  Issue： 11  Page： 1446  Publication year： 2019 
JST Material Number： U7155A  ISSN： 2073-4409  Document type： Article
Article type： 文献レビュー  Country of issue： Switzerland (CHE)  Language： ENGLISH (EN)

Abstract/Point： In contrast to the programmed ...

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Thesaurus term： heredity ,  gene ,  phenotype ,  mitosis ,  *senile change ,  fingerprint ,  characterization ,  cell aging ,  epigenetics
Semi thesaurus term： インフラマソーム ,  複製老化 , 【Automatic Indexing@JST】

Author keywords (8)： aging ,  amitosenescence ,  brain ,  epigenetics ,  inflamm-aging ,  rejuvenation ,  replicative senescence ,  genetic program

JST classification (2)： Aging and death  (EJ16040S) ,  Cell physiology in general  (EF02010S)

Reference (180)：

• Niccoli, T.; Partridge, L. Ageing as a Risk Factor for Disease. Curr. Boil. 2012, 22, R741-R752.
• Aramillo Irizar, P.; Schauble, S.; Esser, D.; Groth, M.; Frahm, C.; Priebe, S.; Baumgart, M.; Hartmann, N.; Marthandan, S.; Menzel, U.; et al. Transcriptomic alterations during ageing reflect the shift from cancer to degenerative diseases in the elderly. Nat. Commun. 2018, 9, 327.
• Penndorf, D.; Witte, O.W.; Kretz, A. DNA plasticity and damage in amyotrophic lateral sclerosis. Neural Regen. Res. 2018, 13, 173-180.
• López-Otín, C.; Blasco, M.A.; Partridge, L.; Serrano, M.; Kroemer, G. The hallmarks of aging. Cell 2013, 153, 1194-1217.
• Campisi, J. Aging, cellular senescence, and cancer. Annu. Rev. Physiol. 2013, 75, 685-705.

Terms in the title (3)： 老化 ,  概念 ,  教訓