Art

J-GLOBAL ID：202102226136463360   Reference number：21A0091901

Genomic landscape in acute myeloid leukemia and its implications in risk classification and targeted therapies

急性骨髄性白血病のゲノム景観とリスク分類および標的療法におけるその意義【JST・京大機械翻訳】

Author (2)： Hou Hsin-An (Division of Hematology, Department of Internal Medicine, National Taiwan University Hospital, National Taiwan University, Taipei, Taiwan) ,  Tien Hwei-Fang (Division of Hematology, Department of Internal Medicine, National Taiwan University Hospital, National Taiwan University, Taipei, Taiwan)
Material： Journal of Biomedical Science (Web)
Volume： 27  Issue： 1  Page： 1-13  Publication year： 2020 
JST Material Number： U7325A  ISSN： 1423-0127  Document type： Article
Article type： 文献レビュー  Country of issue： United Kingdom (GBR)  Language： ENGLISH (EN)

Abstract/Point： Acute myeloid leukemia (AML) i...

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Thesaurus term： Heredity ,  *genome ,  Prognosis ,  surface antigen ,  biomarker ,  pathogenesis ,  *acute myeloid leukemia ,  *molecular target therapy ,  Individualized Medicine ,  Genetic Markers ,  stratification of risk ,  Genetic Variation
Semi thesaurus term： genetic variation ,  悪性腫瘍 ,  *リスク分類 ,  臨床的特徴 , 【Automatic Indexing@JST】

Author keywords (4)： Acute myeloid leukemia ,  Genetic markers ,  Risk stratification ,  Therapeutics

JST classification (1)： Blood cell tumors(=neoplasms)  (GK04000M)

Reference (167)：

• Blood; The 2016 revision to the World Health Organization classification of myeloid neoplasms and acute leukemia; DA Arber, A Orazi, R Hasserjian; 127; 2016; 2391-2405; citation_id=CR1
• N Engl J Med; Acute myeloid leukemia; H Dohner, DJ Weisdorf, CD Bloomfield; 373; 2015; 1136-1152; citation_id=CR2
• Surveillance, epidemiology, and end results (SEER) program cancer stat facts: Leukemia - acute myeloid leukemia (AML)https://seer.cancer.gov/statfacts/html/amyl.html; 2018, Accessed 18 Apr 2019.
• Blood Rev; Epidemiology of acute myeloid leukemia: recent progress and enduring challenges; RM Shallis, R Wang, A Davidoff, X Ma, AM Zeidan; 36; 2019; 70-87; citation_id=CR4
• Blood; AML1/RUNX1 mutations in 470 adult patients with de novo acute myeloid leukemia: prognostic implication and interaction with other gene alterations; JL Tang, HA Hou, CY Chen; 114; 2009; 5352-5361; citation_id=CR5

Terms in the title (5)： 急性骨髄性白血病 ,  ゲノム ,  景観 ,  リスク分類 ,  標的療法