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J-GLOBAL ID：202102228883207285   Reference number：21A0217537

Quantitative analysis of β1,6GlcNAc-branched N-glycans on β4 integrin in cutaneous squamous cell carcinoma

皮膚扁平上皮癌におけるβ4インテグリン上のβ1,6GlcNAc分岐N-グリカンの定量分析

Author (6)： Kariya Yoshinobu (Department of Biochemistry, Fukushima Medical University School of Medicine) ,  Oyama Midori (Department of Biochemistry, Fukushima Medical University School of Medicine) ,  Ohtsuka Mikio (Department of Dermatology, Fukushima Medical University School of Medicine) ,  Kikuchi Nobuyuki (Department of Dermatology, Fukushima Medical University School of Medicine) ,  Hashimoto Yasuhiro (Department of Biochemistry, Fukushima Medical University School of Medicine) ,  Yamamoto Toshiyuki (Department of Dermatology, Fukushima Medical University School of Medicine)
Material： Fukushima Journal of Medical Science (Web)  (Fukushima J Med Sci (Web))
Volume： 66  Issue： 3  Page： 119-123(J-STAGE)  Publication year： 2020 
JST Material Number： U0218A  ISSN： 2185-4610  Document type： Article
Article type： 原著論文  Country of issue： Japan (JPN)  Language： ENGLISH (EN)

Thesaurus term： human ,...
Semi thesaurus term： *beta4 integrin ,...

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Author keywords (7)： β4 integrin ,  glycosylation ,  squamous cell carcinoma ,  β1 ,  6GlcNAc-branched ,  N-glycan ,  ELISA

JST classification (3)： Chemistry,biochemistry and pathology of tumors(=neoplasms)  (GE02030N) ,  Biological function  (EB06020T) ,  Skin tumors(=neoplasms)  (GF04000X)

Reference (21)：

• 1. Litjens SH, de Pereda JM, Sonnenberg A. Current insights into the formation and breakdown of hemidesmosomes. Trends in Cell Biol, 16:376-383, 2006.
• 2. Ko MS, Marinkovich MP. Role of dermal-epidermal basement membrane zone in skin, cancer, and developmental disorders. Dermatol Clin, 28:1-16, 2010.
• 3. Kariya Y, Kariya Y, Gu J. Laminin-332 and Integrins:Signaling Platform for Cell Adhesion and Migration and its Regulation by N-glycosylation. In:Laminins:Structure, Biological Activity and Role in Disease, Ch. 29:29-51, 2013.
• 4. Kariya Y, Kariya Y, Gu J. Roles of Integrin α6β4 Glycosylation in Cancer. Cancers, 9, 2017.
• 5. Stewart RL, O’Connor KL. Clinical significance of the integrin α6β4 in human malignancies. Lab invest, 95:976-986, 2015.

Terms in the title (5)： 皮膚扁平上皮癌 ,  β4インテグリン ,  分岐 ,  N-グリカン ,  定量分析