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J-GLOBAL ID：202102229066899799   Reference number：21A2092791

Sulfur Compounds Inhibit High Glucose-Induced Inflammation by Regulating NF-κB Signaling in Human Monocytes

硫黄化合物はヒト単球においてNF-κBシグナリングを調節することにより高グルコース誘導炎症を阻害する【JST・京大機械翻訳】

Author (10)： Jo Eun Seong (Department of Pathology, School of Medicine, Institute of Biomedical Science and Technology, Konkuk University, Chungju 27478, Korea) ,  Sp Nipin (Department of Pathology, School of Medicine, Institute of Biomedical Science and Technology, Konkuk University, Chungju 27478, Korea) ,  Kang Dong Young (Department of Pathology, School of Medicine, Institute of Biomedical Science and Technology, Konkuk University, Chungju 27478, Korea) ,  Rugamba Alexis (Department of Pathology, School of Medicine, Institute of Biomedical Science and Technology, Konkuk University, Chungju 27478, Korea) ,  Kim Il Ho (Nara Bio Co., Ltd., Jeonju, North Jeolla 54852, Korea) ,  Bae Se Won (Green Chemistry & Materials Group, Korea Institute of Industrial Technology (KITECH), Cheonan 31056, Korea) ,  Bae Se Won (Department of Green Process and System Engineering, Korea University of Science & Technology (UST), Cheonan 31056, Korea) ,  Liu Qing (Jilin Green Food Engineering Research Institute, Changchun 130000, China) ,  Jang Kyoung-Jin (Department of Pathology, School of Medicine, Institute of Biomedical Science and Technology, Konkuk University, Chungju 27478, Korea) ,  Yang Young Mok (Department of Pathology, School of Medicine, Institute of Biomedical Science and Technology, Konkuk University, Chungju 27478, Korea)
Material： Molecules (Web)
Volume： 25  Issue： 10  Page： 2342  Publication year： 2020 
JST Material Number： U7014A  ISSN： 1420-3049  CODEN： MOLEFW  Document type： Article
Article type： 原著論文  Country of issue： Switzerland (CHE)  Language： ENGLISH (EN)

Abstract/Point： High glucose-induced inflammat...

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Thesaurus term： DNA ,  *inflammation ,  anti-inflammatory action ,  *sulfur ,  flow cytometry ,  ELISA ,  interleukin ,  type 2 diabetes mellitus ,  Western blotting ,  *NF-kappaB ,  inflammatory cytokine ,  real time polymerase chain reaction ,  hexose ,  aldose
Semi thesaurus term： Toll様受容体2 ,  Toll様受容体4 , 【Automatic Indexing@JST】

Author keywords (7)： High glucose ,  Diabetes ,  TLRs ,  NF-κB ,  Canonical pathway ,  PKC pathway ,  Proinflammatory cytokines

JST classification (1)： Basic research of drugs acting on carbohydrate metabolism  (GW13020Q)

Substance index (1)： Glucose

Reference (44)：

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• Brownlee, M. The Pathobiology of Diabetic Complications: A Unifying Mechanism. Diabetes 2005, 54, 1615-1625.

Terms in the title (9)： 硫黄化合物 ,  ヒト単球 ,  NF-κB ,  シグナリング ,  調節 ,  グルコース ,  誘導 ,  炎症 ,  阻害