Art

J-GLOBAL ID：202102229293618064   Reference number：21A0830001

Methylation-Based Therapies for Colorectal Cancer

結腸直腸癌に対するメチル化に基づく治療【JST・京大機械翻訳】

Author (11)： Cervena Klara (Department of Molecular Biology of Cancer, Institute of Experimental Medicine, Videnska 1083, 14 200 Prague, Czech Republic) ,  Cervena Klara (Institute of Biology and Medical Genetics, First Faculty of Medicine, Charles University, Albertov 4, 128 00 Prague, Czech Republic) ,  Siskova Anna (Department of Molecular Biology of Cancer, Institute of Experimental Medicine, Videnska 1083, 14 200 Prague, Czech Republic) ,  Siskova Anna (Institute of Biology and Medical Genetics, First Faculty of Medicine, Charles University, Albertov 4, 128 00 Prague, Czech Republic) ,  Buchler Tomas (Department of Oncology, First Faculty of Medicine, Charles University and Thomayer Hospital, Videnska 800, 140 59 Prague, Czech Republic) ,  Vodicka Pavel (Department of Molecular Biology of Cancer, Institute of Experimental Medicine, Videnska 1083, 14 200 Prague, Czech Republic) ,  Vodicka Pavel (Institute of Biology and Medical Genetics, First Faculty of Medicine, Charles University, Albertov 4, 128 00 Prague, Czech Republic) ,  Vodicka Pavel (Biomedical Centre, Faculty of Medicine in Pilsen, Charles University, Alej Svobody 76, 323 00 Pilsen, Czech Republic) ,  Vymetalkova Veronika (Department of Molecular Biology of Cancer, Institute of Experimental Medicine, Videnska 1083, 14 200 Prague, Czech Republic) ,  Vymetalkova Veronika (Institute of Biology and Medical Genetics, First Faculty of Medicine, Charles University, Albertov 4, 128 00 Prague, Czech Republic) ,  Vymetalkova Veronika (Biomedical Centre, Faculty of Medicine in Pilsen, Charles University, Alej Svobody 76, 323 00 Pilsen, Czech Republic)
Material： Cells (Web)
Volume： 9  Issue： 6  Page： 1540  Publication year： 2020 
JST Material Number： U7155A  ISSN： 2073-4409  Document type： Article
Article type： 文献レビュー  Country of issue： Switzerland (CHE)  Language： ENGLISH (EN)

Abstract/Point： Colorectal carcinogenesis (CRC...

Register(free) or Log In to access     To see more with JDream III (charged).   {{ this.onShowAbsJLink("http://jdream3.com/lp/jglobal/index.html?docNo=21A0830001&from=J-GLOBAL&jstjournalNo=U7155A") }}

Thesaurus term： *methylation ,  DNA ,  heredity ,  carcinogenesis ,  drug therapy ,  DNA methyltransferase ,  prognosis ,  gene expression ,  pathogenesis
Semi thesaurus term： DNAメチル化 ,  治療反応性 ,  *結腸直腸癌 ,  治療標的 ,  過メチル化 ,  *結腸直腸 , 【Automatic Indexing@JST】

Author keywords (4)： colorectal cancer ,  methylation ,  DNMT inhibitors ,  therapy

JST classification (1)： Tumors(=neoplasms)of digestive system  (GH04000D)

Reference (232)：

• Lazennec, G.; Lam, P.Y. Recent discoveries concerning the tumor-mesenchymal stem cell interactions. Biochim. Biophys. Acta Rev. Cancer 2016, 1866, 290-299.
• El Bairi, K.; Tariq, K.; Himri, I.; Jaafari, A.; Smaili, W.; Kandhro, A.H.; Gouri, A.; Ghazi, B. Decoding colorectal cancer epigenomics. Cancer Genet. 2018, 220, 49-76.
• Farkas, S.; Vymetalkova, V.; Vodickova, L.; Vodicka, P.; Nilsson, T.K. DNA methylation changes in genes frequently mutated in sporadic colorectal cancer and in the DNA repair and Wnt/β-catenin signaling pathway genes. Epigenomics 2014, 6, 179-191.
• Vymetalkova, V.; Vodicka, P.; Pardini, B.; Rosa, F.; Levy, M.; Schneiderova, M.; Liska, V.; Vodickova, L.; Nilsson, T.K.; Farkas, S. Epigenome-wide analysis of DNA methylation reveals a rectal cancer-specific epigenomic signature. Epigenomics 2016, 8, 1193-1207.
• Vymetalkova, V.; Vodicka, P.; Vodenkova, S.; Alonso, S.; Schneider-Stock, R. DNA methylation and chromatin modifiers in colorectal cancer. Mol. Asp. Med. 2019, 69, 73-92.

Terms in the title (3)： 結腸直腸癌 ,  メチル化 ,  治療