Art

J-GLOBAL ID：202102229868433362   Reference number：21A2822933

Reduced CCR6⁺IL-17A⁺Treg Cells in Blood and CCR6-Dependent Accumulation of IL-17A⁺Treg Cells in Lungs of Patients With Allergic Asthma

アレルギー性喘息患者の肺におけるIL-17A+Treg細胞の血液およびCCR6依存性蓄積におけるCCR6+IL-17A+Treg細胞の減少【JST・京大機械翻訳】

Author (11)： Shen Xiaokun (1Institute of Translation Medicine, First Affiliated Hospital of Jinzhou Medical University, Jinzhou, China) ,  Zhang Huiyun (2Institute of Translation Medicine, Shenyang Medical College, Shenyang, China) ,  Xie Hua (3People’s Liberation Army (PLA) Center of Respiratory and Allergic Disease Diagnosing Management, General Hospital of Shenyang Military Area Command, Shenyang, China) ,  Chen Liping (4Respiratory Medicine Department, Second Affiliated Hospital of Shenyang Medical College, Shenyang, China) ,  Li Shinan (1Institute of Translation Medicine, First Affiliated Hospital of Jinzhou Medical University, Jinzhou, China) ,  Zheng Junjuan (5State Key Laboratory of Genetic Resources and Evolution/Key Laboratory of Healthy Aging Research of Yunnan Province, Kunming Institute of Zoology, Chinese Academy of Sciences, Kunming, China) ,  Chai Ruonan (3People’s Liberation Army (PLA) Center of Respiratory and Allergic Disease Diagnosing Management, General Hospital of Shenyang Military Area Command, Shenyang, China) ,  Wang Zhao (1Institute of Translation Medicine, First Affiliated Hospital of Jinzhou Medical University, Jinzhou, China) ,  Zang Yanyan (1Institute of Translation Medicine, First Affiliated Hospital of Jinzhou Medical University, Jinzhou, China) ,  He Shaoheng (1Institute of Translation Medicine, First Affiliated Hospital of Jinzhou Medical University, Jinzhou, China) ,  He Shaoheng (2Institute of Translation Medicine, Shenyang Medical College, Shenyang, China)
Material： Frontiers in Immunology (Web)
Volume： 12  Page： 710750  Publication year： 2021 
JST Material Number： U7074A  ISSN： 1664-3224  Document type： Article
Article type： 原著論文  Country of issue： Switzerland (CHE)  Language： ENGLISH (EN)

Abstract/Point： Human regulatory T (Treg) cell...

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Thesaurus term： RNA ,  air duct(respiration) ,  *asthma ,  human(primates) ,  cell fractionation ,  flow cytometry ,  pathological state ,  in vitro experiment ,  cell migration ,  peripheral blood ,  chemokine ,  pathogenesis ,  *regulatory T cell
Semi thesaurus term： *インターロイキン17 ,  Th17細胞 , 【Automatic Indexing@JST】

Author keywords (5)： asthma ,  HDM ,  CCR6⁺ Treg ,  IL-17 ,  CCL20

JST classification (2)： Immunological reaction in general  (ED03010T) ,  Immunologic diseases,allergic diseases in general.  (GD04010C)

Reference (47)：

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• Walker JA, McKenzie ANJ. TH2 Cell Development and Function. Nat Rev Immunol (2018) 18(2):121-33. doi: doi: 10.1038/nri.2017.118
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• Boonpiyathad T, Sozener ZC, Akdis M, Akdis CA. The Role of Treg Cell Subsets in Allergic Disease. Asian Pacific J Allergy Immunol (2020) 38(3):139-49. doi: doi: 10.12932/AP-030220-0754

Terms in the title (7)： アレルギー性喘息 ,  患者 ,  肺 ,  血液 ,  CCR6 ,  依存性 ,  蓄積