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J-GLOBAL ID：202102230795668521   Reference number：21A0070968

Niclosamide activates the AMP-activated protein kinase complex containing the β2 subunit independently of AMP

ニクロサミドはAMPとは無関係にβ2サブユニットを含むAMP活性化蛋白質キナーゼ複合体を活性化する【JST・京大機械翻訳】

Author (6)： Suzuki Tsukasa (Department of Agricultural Chemistry, Faculty of Applied Biosciences, Tokyo University of Agriculture, Setagaya-ku, Tokyo, 156-8502, Japan) ,  Kojima Momoko (Department of Agricultural Chemistry, Faculty of Applied Biosciences, Tokyo University of Agriculture, Setagaya-ku, Tokyo, 156-8502, Japan) ,  Matsumoto Yu (Department of Agricultural Chemistry, Faculty of Applied Biosciences, Tokyo University of Agriculture, Setagaya-ku, Tokyo, 156-8502, Japan) ,  Kobayashi Ken-Ichi (Department of Agricultural Chemistry, Faculty of Applied Biosciences, Tokyo University of Agriculture, Setagaya-ku, Tokyo, 156-8502, Japan) ,  Inoue Jun (Department of Agricultural Chemistry, Faculty of Applied Biosciences, Tokyo University of Agriculture, Setagaya-ku, Tokyo, 156-8502, Japan) ,  Yamamoto Yuji (Department of Agricultural Chemistry, Faculty of Applied Biosciences, Tokyo University of Agriculture, Setagaya-ku, Tokyo, 156-8502, Japan)
Material： Biochemical and Biophysical Research Communications  (BBRC)
Volume： 533  Issue： 4  Page： 758-763  Publication year： 2020 
JST Material Number： B0118A  ISSN： 0006-291X  Document type： Article
Article type： 短報  Country of issue： Netherlands (NLD)  Language： ENGLISH (EN)

Abstract/Point： AMP-activated protein kinase (...

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Thesaurus term： dissimilation ,  sensitivity ,  parasitic insect ,  anthelmintic ,  blood glucose ,  fatty liver ,  diabetes mellitus ,  mitochondria ,  *subunit ,  *complex(substance) ,  metabolic syndrome ,  aromatic amine ,  aromatic carboxylic acid ,  aromatic nitro compound ,  phenolic compound ,  aromatic chlorine compound ,  carboxamide ,  hydroxy acid ,  amino acid ,  aliphatic amine ,  aliphatic carboxylic acid ,  primary amine
Semi thesaurus term： *AMP活性化蛋白質キナーゼ ,  治療標的 , 【Automatic Indexing@JST】

Author keywords (5)： AMPK ,  AMPKβ2 subunit ,  Niclosamide ,  Diabetes ,  Metformin

JST classification (2)： Biological function  (EB03040U) ,  Cell physiology in general  (EF02010S)

Substance index (2)： Niclosamide ,  Alanine

Terms in the title (6)： ニクロサミド ,  AMP ,  サブユニット ,  AMP活性化蛋白質キナーゼ ,  複合体 ,  活性化