Art

J-GLOBAL ID：202102231240450189   Reference number：21A0194506

Gap junctions amplify TRPV4 activation-initiated cell injury via modification of intracellular Ca²⁺ and Ca²⁺-dependent regulation of TXNIP

ギャップ結合はTXNIPの細胞内Ca2+とCa2+依存性調節の修飾を介してTRPV4活性化開始細胞傷害を増幅する【JST・京大機械翻訳】

Author (6)： Zhang Xiling (Department of Urology, The Fourth Affiliated Hospital of China Medical University, Shenyang, China) ,  Zhang Xiling (Division of Molecular Signaling, Department of the Advanced Biomedical Research, Interdisciplinary Graduate School of Medicine, University of Yamanashi, Chuo, Japan) ,  Mao Zhimin (Division of Molecular Signaling, Department of the Advanced Biomedical Research, Interdisciplinary Graduate School of Medicine, University of Yamanashi, Chuo, Japan) ,  Huang Yanru (Division of Molecular Signaling, Department of the Advanced Biomedical Research, Interdisciplinary Graduate School of Medicine, University of Yamanashi, Chuo, Japan) ,  Zhang Zhen (Division of Molecular Signaling, Department of the Advanced Biomedical Research, Interdisciplinary Graduate School of Medicine, University of Yamanashi, Chuo, Japan) ,  Yao Jian (Division of Molecular Signaling, Department of the Advanced Biomedical Research, Interdisciplinary Graduate School of Medicine, University of Yamanashi, Chuo, Japan)
Material： Channels
Volume： 14  Issue： 1  Page： 246-256  Publication year： 2020 
JST Material Number： W2370A  ISSN： 1933-6950  Document type： Article
Article type： 原著論文  Country of issue： United Kingdom (GBR)  Language： ENGLISH (EN)

Abstract/Point： ABSTRACT: The elevated intrace...

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Thesaurus term： interaction ,  chelating reagent ,  epithelium ,  kidney tubule ,  channel ,  thioredoxin ,  *gap junction ,  Down-Regulation ,  Cell Death ,  oxidative stress ,  siRNA ,  Connexin 43 ,  Cell damage ,  controlling element ,  membrane and film ,  histomembrane ,  *Cell Physiological Phenomena
Semi thesaurus term： アゴニスト , 【Automatic Indexing@JST】

Author keywords (5)： TRPV4 ,  connexin43 ,  TXNIP ,  oxidative stress ,  cell injury

JST classification (2)： Receptors on cell membrane  (EF04030C) ,  Transport of cell membrane  (EF04020R)

Terms in the title (10)： ギャップ結合 ,  TXNIP ,  依存性 ,  調節 ,  修飾 ,  TRPV4 ,  活性化 ,  細胞 ,  傷害 ,  増幅