Art

J-GLOBAL ID：202102231754753399   Reference number：21A0137846

The Impact of Hemodialysis and Liver Cirrhosis on the Plasma Concentrations of Tyrosine Kinase Inhibitors in a Patient with Chronic Myeloid Leukemia

慢性骨髄性白血病患者におけるチロシンキナーゼ阻害剤の血漿濃度に対する血液透析と肝硬変の影響

Author (15)： Taniguchi Yasuhiro (Departments of Hematology and Rheumatology, Faculty of Medicine, Kindai University Hospital, Japan) ,  Takahashi Naoto (Departments of Hematology, Nephrology, and Rheumatology, Akita University Graduate School of Medicine, Japan) ,  Miura Masatomo (Department of Pharmacy, Akita University Hospital, Japan) ,  Hirase Chikara (Departments of Hematology and Rheumatology, Faculty of Medicine, Kindai University Hospital, Japan) ,  Sueda Sanae (Department of Hematology, PL General Hospital, Japan) ,  Espinoza Jorge Luis (Faculty of Health Sciences, Institute of Medical, Pharmaceutical and Health Sciences, Kanazawa University, Japan) ,  Espinoza Jorge Luis (Faculty of Medicine, UNIDES University, Nicaragua) ,  Rai Shinya (Departments of Hematology and Rheumatology, Faculty of Medicine, Kindai University Hospital, Japan) ,  Nakayama Shoko (Departments of Hematology and Rheumatology, Faculty of Medicine, Kindai University Hospital, Japan) ,  Serizawa Kentaro (Departments of Hematology and Rheumatology, Faculty of Medicine, Kindai University Hospital, Japan) ,  Kumode Takahiro (Departments of Hematology and Rheumatology, Faculty of Medicine, Kindai University Hospital, Japan) ,  Watatani Yosaku (Departments of Hematology and Rheumatology, Faculty of Medicine, Kindai University Hospital, Japan) ,  Morita Yasuyoshi (Departments of Hematology and Rheumatology, Faculty of Medicine, Kindai University Hospital, Japan) ,  Tanaka Hirokazu (Departments of Hematology and Rheumatology, Faculty of Medicine, Kindai University Hospital, Japan) ,  Matsumura Itaru (Departments of Hematology and Rheumatology, Faculty of Medicine, Kindai University Hospital, Japan)
Material： Internal Medicine (Web)  (Intern Med (Web))
Volume： 59  Issue： 21  Page： 2745-2749(J-STAGE)  Publication year： 2020 
JST Material Number： U0033A  ISSN： 1349-7235  Document type： Article
Article type： 原著論文  Country of issue： Japan (JPN)  Language： ENGLISH (EN)

Thesaurus term： human(primates) ,...
Semi thesaurus term： *tyrosine kinase inhibitor ,...

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Author keywords (5)： dasatinib ,  bosutinib ,  hemodialysis ,  liver cirrhosis ,  plasma concentrations

JST classification (4)： Drug therapy(=pharmacotherapy)for tumors  (GE03032C) ,  Blood cell tumors(=neoplasms)  (GK04000M) ,  Digestive system diseases  (GH03000W) ,  Urogenital diseases  (GM03000L)

Substance index (2)： Dasatinib ,  SKI-606

Reference (23)：

• 1. Druker BJ, Guihot F, O'Brien SG, et al. Five-year follow-up of patients receiving imatinib for chronic myeloid leukemia. N Engl J Med 355: 2408-2417, 2006.
• 2. Lang K, McGarry LJ, Huang H, Dorer D, Kaufman E, Knopf K. Mortality and vascular events among elderly patients with chronic myeloid leukemia: a retrospective analysis of linked SEER-medicare data. Clin Lymphoma Myeloma Leuk 16: 275-285.e1, 2016.
• 3. Saussele S, Krauss MP, Hehlmann R, et al. Impact of comorbidities on overall survival in patients with chronic myeloid leukemia: results of the randomized CML study IV. Blood 126: 42-49, 2015.
• 4. Sohn SK, Oh SJ, Kim BS, et al. Trough plasma imatinib levels are correlated with optimal cytogenetic responses at 6 months after treatment with standard dose of imatinib in newly diagnosed chronic myeloid leukemia. Leuk Lymphoma 52: 1024-1029, 2011.
• 5. Giles FJ, Yin OQ, Sallas WM, et al. Nilotinib population pharmacokinetics and exposure-response analysis in patients with imatinib-resistant or -intolerant chronic myeloid leukemia. Eur J Clin Pharmacol 69: 813-823, 2013.

Terms in the title (6)： 慢性骨髄性白血病 ,  患者 ,  チロシンキナーゼ阻害剤 ,  血漿濃度 ,  血液透析 ,  肝硬変