Art

J-GLOBAL ID：202102232040080831   Reference number：21A0295098

Intrinsic braking role of descending locus coeruleus noradrenergic neurons in acute and chronic itch in mice

マウスの急性および慢性掻痒における下行青斑ノルアドレナリン作動性ニューロンの固有ブレーキの役割【JST・京大機械翻訳】

Author (11)： Koga Keisuke (Department of Life Innovation, Graduate School of Pharmaceutical Sciences, Kyushu University, Fukuoka, Japan) ,  Koga Keisuke (Department of Neurophysiology, Hyogo College of Medicine, Nishinomiya, Japan) ,  Shiraishi Yuto (Department of Life Innovation, Graduate School of Pharmaceutical Sciences, Kyushu University, Fukuoka, Japan) ,  Shiraishi Yuto (Department of Molecular and System Pharmacology, Graduate School of Pharmaceutical Sciences, Kyushu University, Fukuoka, Japan) ,  Yamagata Ryo (Department of Life Innovation, Graduate School of Pharmaceutical Sciences, Kyushu University, Fukuoka, Japan) ,  Tozaki-Saitoh Hidetoshi (Department of Life Innovation, Graduate School of Pharmaceutical Sciences, Kyushu University, Fukuoka, Japan) ,  Tozaki-Saitoh Hidetoshi (Department of Molecular and System Pharmacology, Graduate School of Pharmaceutical Sciences, Kyushu University, Fukuoka, Japan) ,  Shiratori-Hayashi Miho (Department of Life Innovation, Graduate School of Pharmaceutical Sciences, Kyushu University, Fukuoka, Japan) ,  Shiratori-Hayashi Miho (Department of Molecular and System Pharmacology, Graduate School of Pharmaceutical Sciences, Kyushu University, Fukuoka, Japan) ,  Tsuda Makoto (Department of Life Innovation, Graduate School of Pharmaceutical Sciences, Kyushu University, Fukuoka, Japan) ,  Tsuda Makoto (Department of Molecular and System Pharmacology, Graduate School of Pharmaceutical Sciences, Kyushu University, Fukuoka, Japan)
Material： Molecular Brain (Web)
Volume： 13  Issue： 1  Page： 1-11  Publication year： 2020 
JST Material Number： U7335A  ISSN： 1756-6606  Document type： Article
Article type： 原著論文  Country of issue： United Kingdom (GBR)  Language： ENGLISH (EN)

Abstract/Point： Itch is defined as an unpleasa...

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Thesaurus term： electric potential ,  *neuron ,  brake ,  synapse ,  spinal cord ,  *pruritus ,  contact dermatitis ,  *locus ceruleus ,  therapeutic planning ,  patch-clamp ,  gene silencing ,  nitrogen heterocyclic compound ,  autacoid ,  primary amine ,  catecholamine ,  aminoalcohol ,  secondary alcohol ,  polyol
Semi thesaurus term： ノルアドレナリン作動性ニューロン ,  *慢性掻痒 , 【Automatic Indexing@JST】

Author keywords (6)： Descending noradrenaline neurons ,  Locus coeruleus ,  Spinal dorsal horn ,  Gastrin-releasing peptide receptor-expressing neurons ,  Itch ,  Mouse

JST classification (2)： Central nervous system  (EJ12030F) ,  Basic neurology  (GN01020W)

Substance index (2)： Histamine ,  Norepinephrine

Reference (46)：

• Physiol Rev; Physiology and pathophysiology of itch; F Cevikbas, EA Lerner; 100; 3; 2020; 945-982; 10.1152/physrev.00017.2019; citation_id=CR1
• Annu Rev Physiol; Spinal circuits for touch, pain, and itch; SC Koch, D Acton, M Goulding; 80; 2018; 189-217; 10.1146/annurev-physiol-022516-034303; citation_id=CR2
• Neuron; Peripheral and central mechanisms of itch; X Dong, X Dong; 98; 3; 2018; 482-494; 10.1016/j.neuron.2018.03.023; citation_id=CR3
• J Allergy Clin Immunol; Itch: from mechanism to (novel) therapeutic approaches; G Yosipovitch, JD Rosen, T Hashimoto; 142; 5; 2018; 1375-1390; 10.1016/j.jaci.2018.09.005; citation_id=CR4
• Nat Commun; Central circuit mechanisms of itch; XJ Chen, YG Sun; 11; 1; 2020; 3052; 10.1038/s41467-020-16859-5; citation_id=CR5

Terms in the title (7)： マウス ,  慢性掻痒 ,  青斑 ,  ノルアドレナリン作動性ニューロン ,  固有 ,  ブレーキ ,  役割