Art

J-GLOBAL ID：202102233436809670   Reference number：21A0097413

NF-κB p65-dependent transcriptional regulation of histone deacetylase 2 contributes to the chronic constriction injury-induced neuropathic pain via the microRNA-183/TXNIP/NLRP3 axis

ヒストンデアセチラーゼ2のNF-κB p65依存性転写調節はマイクロRNA-183/TXIP/NLRP3軸を介して慢性狭窄損傷誘発神経障害性疼痛に寄与する【JST・京大機械翻訳】

Author (4)： Miao Jiamin (Department of Anesthesiology, Sir Run Run Shaw Hospital, Zhejiang University School of Medicine, Hangzhou, China) ,  Zhou Xuelong (Department of Anesthesiology, The First Affiliated Hospital, College of Medicine, Zhejiang University, Hangzhou, China) ,  Ji Tianjiao (Laboratory for Biomaterials and Drug Delivery, Department of Anesthesiology, Boston Children’s Hospital, Harvard Medical School, Boston, USA) ,  Chen Gang (Department of Anesthesiology, Sir Run Run Shaw Hospital, Zhejiang University School of Medicine, Hangzhou, China)
Material： Journal of Neuroinflammation (Web)
Volume： 17  Issue： 1  Page： 1-13  Publication year： 2020 
JST Material Number： U7329A  ISSN： 1742-2094  Document type： Article
Article type： 原著論文  Country of issue： United Kingdom (GBR)  Language： ENGLISH (EN)

Abstract/Point： Neuropathic pain is related to...

Register(free) or Log In to access     To see more with JDream III (charged).   {{ this.onShowAbsJLink("http://jdream3.com/lp/jglobal/index.html?docNo=21A0097413&from=J-GLOBAL&jstjournalNo=U7329A") }}

Thesaurus term： interaction ,  spinal cord ,  rat ,  promoter(genetics) ,  glia cell ,  down-regulation ,  up-regulation ,  *NF-kappaB ,  inflammatory cytokine
Semi thesaurus term： *神経障害性疼痛 ,  *p65 ,  *転写調節 ,  炎症反応 ,  インフラマソーム ,  ミクログリア細胞 , 【Automatic Indexing@JST】

Author keywords (7)： Neuropathic pain ,  Chronic constriction injury ,  NF-κB p65 ,  Histone deacetylase 2 ,  microRNA-183 ,  TXNIP ,  NLRP3

JST classification (1)： Basic neurology  (GN01020W)

Reference (24)：

• Continuum (Minneap Minn).; Neuropathic pain; LA Zilliox; 23; 2017; 512-532; citation_id=CR1
• J Endocrinol.; Urotensin II inhibitor eases neuropathic pain by suppressing the JNK/NF-kappaB pathway; J Li, PP Zhao, T Hao, D Wang, Y Wang, YZ Zhu, YQ Wu, CH Zhou; 232; 2017; 165-174; 10.1530/JOE-16-0255; citation_id=CR2
• Nat Rev Dis Primers.; Neuropathic pain; L Colloca, T Ludman, D Bouhassira, R Baron, AH Dickenson, D Yarnitsky, R Freeman, A Truini, N Attal, NB Finnerup; 3; 2017; 17002; 10.1038/nrdp.2017.2; citation_id=CR3
• Spinal Cord.; Spinal sample showing p-JNK and P38 associated with the pain signaling transduction of glial cell in neuropathic pain; J Cao, JS Wang, XH Ren, WD Zang; 53; 2015; 92-97; 10.1038/sc.2014.188; citation_id=CR4
• CNS Neurosci Ther.; Effects of oxymatrine on the neuropathic pain induced by chronic constriction injury in mice; HY Liu, YX Li, YJ Hao, HY Wang, XY Dai, T Sun, JQ Yu; 18; 2012; 1030-1032; 10.1111/cns.12026; citation_id=CR5

Terms in the title (9)： ヒストンデアセチラーゼ2 ,  NF-κB ,  p65 ,  依存性 ,  転写調節 ,  NLRP3 ,  慢性狭窄損傷 ,  誘発 ,  神経障害性疼痛