Art

J-GLOBAL ID：202102233767091953   Reference number：21A0804736

Nitric Oxide (NO) and NO Synthases (NOS)-Based Targeted Therapy for Colon Cancer

Colon癌に対する一酸化窒素(NO)とNOシンターゼ(NOS)に基づく標的療法【JST・京大機械翻訳】

Author (7)： Wang Hao (College of Laboratory Medicine, Jilin Medical University, Jilin 132013, China) ,  Wang Liye (Department of Pharmacological and Pharmaceutical Science, College of Pharmacy, University of Houston, Houston, TX, 77204, USA) ,  Xie Zuoxu (Department of Pharmacological and Pharmaceutical Science, College of Pharmacy, University of Houston, Houston, TX, 77204, USA) ,  Zhou Shuang (Department of Pharmacological and Pharmaceutical Science, College of Pharmacy, University of Houston, Houston, TX, 77204, USA) ,  Li Yan (Department of Pharmacological and Pharmaceutical Science, College of Pharmacy, University of Houston, Houston, TX, 77204, USA) ,  Zhou Yue (Department of Statistics, North Dakota University, Fargo, ND 58105, USA) ,  Sun Meiyan (College of Laboratory Medicine, Jilin Medical University, Jilin 132013, China)
Material： Cancers (Web)
Volume： 12  Issue： 7  Page： 1881  Publication year： 2020 
JST Material Number： U7153A  ISSN： 2072-6694  Document type： Article
Article type： 文献レビュー  Country of issue： Switzerland (CHE)  Language： ENGLISH (EN)

Abstract/Point： Colorectal cancer (CRC) is one...

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Thesaurus term： network ,  inflammation ,  colon ,  tumor ,  carcinogenesis ,  *nitrogen monoxide ,  targeting ,  colonic neoplasm ,  *nitric oxide synthase ,  catenin ,  *molecular target therapy
Semi thesaurus term： 悪性腫瘍 ,  内因性 ,  結腸直腸癌 ,  過剰発現 , 【Automatic Indexing@JST】

Author keywords (11)： nitric oxide ,  NO ,  NO synthases ,  NOS ,  iNOS ,  targeted therapy ,  chemoprevention ,  NO delivery system ,  colon cancer ,  clinical manifestation ,  clinical implication

JST classification (2)： Cell physiology in general  (EF02010S) ,  Tumors(=neoplasms)of digestive system  (GH04000D)

Reference (161)：

• Wang, L.; Cho, K.B.; Li, Y.; Tao, G.; Xie, Z.; Guo, B. Long Noncoding RNA (lncRNA)-Mediated competing endogenous rna networks provide novel potential biomarkers and therapeutic targets for colorectal cancer. Int. J. Mol. Sci. 2019, 20, 5758.
• Siegel, R.L.; Miller, K.D.; Jemal, A. Cancer statistics, 2020. Ca Cancer J. Clin. 2020, 70, 7-30.
• Shimokawa, M.; Ohta, Y.; Nishikori, S.; Matano, M.; Takano, A.; Fujii, M.; Date, S.; Sugimoto, S.; Kanai, T.; Sato, T. Visualization and targeting of LGR5(+) human colon cancer stem cells. Nature 2017, 545, 187-192.
• Yin, H.; Fang, J.; Liao, L.; Maeda, H.; Su, Q. Upregulation of heme oxygenase-1 in colorectal cancer patients with increased circulation carbon monoxide levels, potentially affects chemotherapeutic sensitivity. Bmc Cancer 2014, 14, 436.
• Clarke, C.N.; Kopetz, E.S. BRAF mutant colorectal cancer as a distinct subset of colorectal cancer: Clinical characteristics, clinical behavior, and response to targeted therapies. J. Gastrointest Oncol. 2015, 6, 660-667.

Terms in the title (5)： 癌 ,  一酸化窒素 ,  NO ,  NOシンターゼ ,  標的療法