Art

J-GLOBAL ID：202102234198633435   Reference number：21A0197236

The Rho kinase 2 (ROCK2)-specific inhibitor KD025 ameliorates the development of pulmonary arterial hypertension

Rhoキナーゼ2(ROCK2)特異的阻害剤KD025は肺動脈高血圧の発症を改善する【JST・京大機械翻訳】

Author (3)： Yamamura Aya (Department of Physiology, Aichi Medical University, 1-1 Yazakokarimata, Nagakute, Aichi, 480-1195, Japan) ,  Nayeem Md Junayed (Department of Physiology, Aichi Medical University, 1-1 Yazakokarimata, Nagakute, Aichi, 480-1195, Japan) ,  Sato Motohiko (Department of Physiology, Aichi Medical University, 1-1 Yazakokarimata, Nagakute, Aichi, 480-1195, Japan)
Material： Biochemical and Biophysical Research Communications  (BBRC)
Volume： 534  Page： 795-801  Publication year： 2021 
JST Material Number： B0118A  ISSN： 0006-291X  Document type： Article
Article type： 短報  Country of issue： Netherlands (NLD)  Language： ENGLISH (EN)

Abstract/Point： Pulmonary arterial hypertensio...

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Thesaurus term： Rattus ,  *Pulmonary Artery ,  pulmonary hypertension ,  in vitro experiment ,  pathogenesis ,  vascular remodeling ,  systolic blood pressure ,  siRNA ,  *ROCK ,  *Rho kinase ,  Right ventricle ,  pulmonary arterial smooth muscle cells ,  Signal Transduction ,  Myomorpha
Semi thesaurus term： cellular signal transduction ,  治療標的 ,  *肺動脈高血圧症 , 【Automatic Indexing@JST】

Author keywords (6)： KD025 ,  Pulmonary artery ,  Pulmonary hypertension ,  Rho kinase ,  ROCK2 ,  Vascular remodeling

JST classification (2)： Cell physiology in general  (EF02010S) ,  Basic research of vasoactive drugs and hypotensive drugs  (GW07040J)

Terms in the title (5)： Rhoキナーゼ2 ,  ROCK2 ,  阻害剤 ,  肺動脈高血圧 ,  発症