Art

J-GLOBAL ID：202102234268026744   Reference number：21A1357788

A Paradigm in Immunochemistry, Revealed by Monoclonal Antibodies to Spatially Distinct Epitopes on Syntenin-1

シンテニン-1上の空間的に異なるエピトープに対するモノクローナル抗体により明らかにした免疫化学のパラダイム【JST・京大機械翻訳】

Author (17)： Johnson Ian R. D. (Mechanisms in Cell Biology and Disease Research Group, School of Pharmacy and Medical Sciences, University of South Australia Cancer Research Institute, University of South Australia, Adelaide, SA 5000, Australia) ,  Johnson Ian R. D. (Adelaide Medical School and Freemasons Foundation Centre for Men’s Health, University of Adelaide, Adelaide, SA 5000, Australia) ,  Sorvina Alexandra (Mechanisms in Cell Biology and Disease Research Group, School of Pharmacy and Medical Sciences, University of South Australia Cancer Research Institute, University of South Australia, Adelaide, SA 5000, Australia) ,  Logan Jessica M. (Mechanisms in Cell Biology and Disease Research Group, School of Pharmacy and Medical Sciences, University of South Australia Cancer Research Institute, University of South Australia, Adelaide, SA 5000, Australia) ,  Moore Courtney R. (Adelaide Medical School and Freemasons Foundation Centre for Men’s Health, University of Adelaide, Adelaide, SA 5000, Australia) ,  Moore Courtney R. (South Australian Health and Medical Research Institute, Adelaide, SA 5000, Australia) ,  Heatlie Jessica K. (Mechanisms in Cell Biology and Disease Research Group, School of Pharmacy and Medical Sciences, University of South Australia Cancer Research Institute, University of South Australia, Adelaide, SA 5000, Australia) ,  Heatlie Jessica K. (Adelaide Medical School and Freemasons Foundation Centre for Men’s Health, University of Adelaide, Adelaide, SA 5000, Australia) ,  Parkinson-Lawrence Emma J. (Mechanisms in Cell Biology and Disease Research Group, School of Pharmacy and Medical Sciences, University of South Australia Cancer Research Institute, University of South Australia, Adelaide, SA 5000, Australia) ,  Selemidis Stavros (Oxidant and Inflammation Biology Group, Chronic Infectious and Inflammatory Diseases Program, School of Health and Biomedical Sciences, RMIT University, Bundoora, VIC 3803, Australia) ,  Selemidis Stavros (Department of Pharmacology, Infection and Immunity Program, Biomedicine Discovery Institute, Monash University, Clayton, VIC 3800, Australia) ,  O'Leary John J. (Department of Histopathology, School of Medicine Trinity College Dublin, Dublin 8, Ireland) ,  O'Leary John J. (Molecular Pathology Laboratory, The Coombe Women and Infants’ University Hospital, Dublin 8, Ireland) ,  Butler Lisa M. (Adelaide Medical School and Freemasons Foundation Centre for Men’s Health, University of Adelaide, Adelaide, SA 5000, Australia) ,  Butler Lisa M. (South Australian Health and Medical Research Institute, Adelaide, SA 5000, Australia) ,  Brooks Douglas A. (Mechanisms in Cell Biology and Disease Research Group, School of Pharmacy and Medical Sciences, University of South Australia Cancer Research Institute, University of South Australia, Adelaide, SA 5000, Australia) ,  Brooks Douglas A. (Department of Histopathology, School of Medicine Trinity College Dublin, Dublin 8, Ireland)
Material： International Journal of Molecular Sciences (Web)  (Int J Mol Sci (Web))
Volume： 20  Issue： 23  Page： 6035  Publication year： 2019 
JST Material Number： U7038A  ISSN： 1422-0067  CODEN： IJMCFK  Document type： Article
Article type： 原著論文  Country of issue： Switzerland (CHE)  Language： ENGLISH (EN)

Abstract/Point： Syntenin-1 is an essential mul...

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Thesaurus term： interaction ,  biosynthesis ,  *antibody ,  prostate gland ,  dyeing ,  cytoskeleton ,  *epitope ,  *monoclonal antibody ,  prostatic tumor ,  endosome ,  atrophy(disease) ,  pathogenesis ,  adaptor protein
Semi thesaurus term： エキソソーム ,  細胞内局在 , 【Automatic Indexing@JST】

Author keywords (4)： syntenin-1 ,  prostate cancer ,  microtubules ,  endosomes

JST classification (1)： Production and application of antigens,antibodies,complements  (ED04030W)

Reference (36)：

• Lin, J.J.; Jiang, H.; Fisher, P.B. Melanoma differentiation associated gene-9, mda-9, is a human gamma interferon responsive gene. Gene 1998, 207, 105-110.
• Philley, J.V.; Kannan, A.; Dasgupta, S. MDA-9/Syntenin Control. J. Cell Physiol. 2016, 231, 545-550.
• Friand, V.; David, G.; Zimmermann, P. Syntenin and syndecan in the biogenesis of exosomes. Biol. Cell. 2015, 107, 331-341.
• Johnson, I.R.; Parkinson-Lawrence, E.J.; Butler, L.M.; Brooks, D.A. Prostate cell lines as models for biomarker discovery: Performance of current markers and the search for new biomarkers. The Prostate 2014, 74, 547-560.
• Johnson, I.R.; Parkinson-Lawrence, E.J.; Keegan, H.; Spillane, C.D.; Barry-O’Crowley, J.; Watson, W.R.; Selemidis, S.; Butler, L.M.; O’Leary, J.J.; Brooks, D.A. Endosomal gene expression: a new indicator for prostate cancer patient prognosis? Oncotarget 2015, 6, 37919-37929.

Terms in the title (5)： シンテニン ,  エピトープ ,  モノクローナル抗体 ,  免疫化学 ,  パラダイム