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J-GLOBAL ID:202102235590963791   Reference number:21A1890197

認知症-最近の動向 治療薬解説 アルツハイマー病に対する疾患修飾薬

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Material:
Volume: 39  Issue:Page: 668-672  Publication year: Jul. 01, 2021 
JST Material Number: G0171B  ISSN: 0287-8445  Document type: Article
Article type: 解説  Country of issue: Japan (JPN)  Language: JAPANESE (JA)
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Clinical application of other drugs acting on central nervous system  ,  Drug therapy(=pharmacotherapy)for nervous system diseases 
Reference (8):
  • Hardy J, Selkoe DJ :The amyloid hypothesis of Alzheimer's disease progress and problems on the road to therapeutics. Science 297 :353-356, 2002
  • Holmes C, Boche D, Wilkinson D, et al :Long-term effects of Abeta42 immunisation in Alzheimer's disease follow-up of a randomised, placebo-controlled phase I trial. Lancet 372 : 216-223, 2008
  • Sevigny J, Chiao P, Bussière T, et al: The antibody aducanumab reduces Aβ plaques in Alzheimer's disease. Nature 537 55-56, 2016
  • Honig LS, Vellas B, Woodward M, et al Trial of Solanezumab for Mild Dementia Due to Alzheimer's Disease. N Engl J Med 378 : 321-330, 2018
  • Mintun MA, Lo AC, Evans CD, et al Donanemab in Early Alzheimer's Disease. N Engl J Med 384 : 1691-1704, 2021
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