Art

J-GLOBAL ID：202102238760443689   Reference number：21A1148427

Immune Memory in Mild COVID-19 Patients and Unexposed Donors Reveals Persistent T Cell Responses After SARS-CoV-2 Infection

軽度のCOVID-19患者と非曝露ドナーにおける免疫記憶はSARS-CoV-2感染後の持続性T細胞応答を明らかにする【JST・京大機械翻訳】

Author (13)： Ansari Asgar (1Vaccine Immunology Laboratory, National Institute of Immunology, New Delhi, India) ,  Arya Rakesh (2Department of Biochemistry, All India Institute of Medical Sciences, New Delhi, India) ,  Sachan Shilpa (1Vaccine Immunology Laboratory, National Institute of Immunology, New Delhi, India) ,  Jha Someshwar Nath (1Vaccine Immunology Laboratory, National Institute of Immunology, New Delhi, India) ,  Kalia Anurag (1Vaccine Immunology Laboratory, National Institute of Immunology, New Delhi, India) ,  Lall Anupam (3Department of Transfusion Medicine, All India Institute of Medical Sciences, New Delhi, India) ,  Sette Alessandro (4Center for Infectious Disease and Vaccine Research, La Jolla Institute for Immunology, La Jolla, CA, United States) ,  Sette Alessandro (5Department of Medicine, Division of Infectious Diseases and Global Public Health, University of California, San Diego, La Jolla, CA, United States) ,  Grifoni Alba (4Center for Infectious Disease and Vaccine Research, La Jolla Institute for Immunology, La Jolla, CA, United States) ,  Weiskopf Daniela (4Center for Infectious Disease and Vaccine Research, La Jolla Institute for Immunology, La Jolla, CA, United States) ,  Coshic Poonam (3Department of Transfusion Medicine, All India Institute of Medical Sciences, New Delhi, India) ,  Sharma Ashok (2Department of Biochemistry, All India Institute of Medical Sciences, New Delhi, India) ,  Gupta Nimesh (1Vaccine Immunology Laboratory, National Institute of Immunology, New Delhi, India)
Material： Frontiers in Immunology (Web)
Volume： 12  Page： 636768  Publication year： 2021 
JST Material Number： U7074A  ISSN： 1664-3224  Document type： Article
Article type： 原著論文  Country of issue： Switzerland (CHE)  Language： ENGLISH (EN)

Abstract/Point： Understanding the causes of th...

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Thesaurus term： *donor ,  glycoprotein ,  human(primates) ,  vaccine ,  India ,  magnitude ,  cell-mediated immunity ,  *T cell ,  CD8 antigen ,  CD4 antigen
Semi thesaurus term： *免疫記憶 ,  被験者 ,  交差反応性 ,  適応免疫 ,  *T細胞応答 , 【Automatic Indexing@JST】

Author keywords (5)： human coronavirus ,  pre-existing immunity ,  CD4⁺ T cells ,  B cells ,  neutralizing antibody

JST classification (1)： Infectious immunity  (ED03030P)

Reference (30)：

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• Le BertNTanATKunasegaranKThamCYLHafeziMChiaA. SARS-CoV-2-specific T cell immunity in cases of COVID-19 and SARS, and uninfected controls. Nature (2020) 584(7821):457-62. doi: doi: 10.1038/s41586-020-2550-z
• BraunJLoyalLFrentschMWendischDGeorgPKurthF. SARS-CoV-2-reactive T cells in healthy donors and patients with COVID-19. Nature (2020) 587(7833):270-74 . doi: doi: 10.1038/s41586-020-2598-9
• MateusJGrifoniATarkeASidneyJRamirezSIDanJM. Selective and cross-reactive SARS-CoV-2 T cell epitopes in unexposed humans. Science (2020) 370(6512):89-94. doi: doi: 10.1126/science.abd3871
• WeiskopfDSchmitzKSRaadsenMPGrifoniAOkbaNMAEndemanH. Phenotype and kinetics of SARS-CoV-2-specific T cells in COVID-19 patients with acute respiratory distress syndrome. Sci Immunol (2020) 5(48):1-10. doi: doi: 10.1126/sciimmunol.abd2071

Terms in the title (8)： 軽度 ,  患者 ,  曝露 ,  ドナー ,  免疫記憶 ,  感染 ,  持続性 ,  T細胞応答