Art

J-GLOBAL ID：202102238958087637   Reference number：21A0899698

Dauricine Attenuates Spatial Memory Impairment and Alzheimer-Like Pathologies by Enhancing Mitochondrial Function in a Mouse Model of Alzheimer’s Disease

ダウリシンはアルツハイマー病のマウスモデルにおいてミトコンドリア機能を増強することにより空間記憶障害とAlzheimer様病理を軽減する【JST・京大機械翻訳】

Author (9)： Chen Chongyang (Shenzhen Key Laboratory of Modern Toxicology, Shenzhen Medical Key Discipline of Health Toxicology (2020-2024), Shenzhen Center for Disease Control and Prevention, Shenzhen, China) ,  Liu Pan (Shenzhen Key Laboratory of Modern Toxicology, Shenzhen Medical Key Discipline of Health Toxicology (2020-2024), Shenzhen Center for Disease Control and Prevention, Shenzhen, China) ,  Wang Jing (Shenzhen Key Laboratory of Modern Toxicology, Shenzhen Medical Key Discipline of Health Toxicology (2020-2024), Shenzhen Center for Disease Control and Prevention, Shenzhen, China) ,  Yu Haitao (Shenzhen Key Laboratory of Modern Toxicology, Shenzhen Medical Key Discipline of Health Toxicology (2020-2024), Shenzhen Center for Disease Control and Prevention, Shenzhen, China) ,  Zhang Zaijun (Key Laboratory of Innovative Chemical Drug Research in Cardio-Cerebrovascular Diseases, Institute of New Drug Research and Guangzhou, Jinan University College of Pharmacy, Guangzhou, China) ,  Liu Jianjun (Shenzhen Key Laboratory of Modern Toxicology, Shenzhen Medical Key Discipline of Health Toxicology (2020-2024), Shenzhen Center for Disease Control and Prevention, Shenzhen, China) ,  Chen Xiao (Shenzhen Key Laboratory of Modern Toxicology, Shenzhen Medical Key Discipline of Health Toxicology (2020-2024), Shenzhen Center for Disease Control and Prevention, Shenzhen, China) ,  Zhu Feiqi (Cognitive Impairment Ward of Neurology Department, The Third Affiliated Hospital of Shenzhen University Medical College, Shenzhen, China) ,  Yang Xifei (Shenzhen Key Laboratory of Modern Toxicology, Shenzhen Medical Key Discipline of Health Toxicology (2020-2024), Shenzhen Center for Disease Control and Prevention, Shenzhen, China)
Material： Frontiers in Cell and Developmental Biology (Web)
Volume： 8  Page： 624339  Publication year： 2020 
JST Material Number： U7062A  ISSN： 2296-634X  Document type： Article
Article type： 原著論文  Country of issue： Switzerland (CHE)  Language： ENGLISH (EN)

Abstract/Point： Alzheimer’s disease (AD) is ch...

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Thesaurus term： alkaloid ,  energy metabolism ,  gluconeogenesis ,  synapse ,  *mitochondria ,  phosphorylation ,  hippocampus ,  plaque ,  *Alzheimer disease ,  *pathological state ,  Western blotting ,  proteomics ,  amyloid beta-protein ,  tau protein ,  amyloid plaque

Author keywords (5)： Alzheimer’s disease ,  dauricine ,  proteomics ,  mitochondrial function ,  synaptic function

JST classification (1)： Basic neurology  (GN01020W)

Reference (35)：

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Terms in the title (8)： ダウリシン ,  アルツハイマー病 ,  マウスモデル ,  ミトコンドリア機能 ,  増強 ,  空間記憶障害 ,  Alzheimer ,  病理