Art

J-GLOBAL ID：202102241363058567   Reference number：21A0197802

Possible involvement of TRPM2 activation in 5-fluorouracil-induced myelosuppression in mice

マウスの5-フルオロウラシル誘発骨髄抑制におけるTRPM2活性化の関与の可能性【JST・京大機械翻訳】

Author (7)： Ishibashi Masaaki (Division of Physiology and Pathology, Faculty of Pharmaceutical Sciences, Teikyo Heisei University, Nakano, Tokyo, 164-8530, Japan) ,  Ishibashi Masaaki (Division of Physiology and Pathology, Department of Pharmacology, Toxicology and Therapeutics, Showa University School of Pharmacy, Shinagawa, Tokyo, 142-8555, Japan) ,  Ishii Masakazu (Division of Physiology and Pathology, Faculty of Pharmaceutical Sciences, Teikyo Heisei University, Nakano, Tokyo, 164-8530, Japan) ,  Ishii Masakazu (Division of Physiology and Pathology, Department of Pharmacology, Toxicology and Therapeutics, Showa University School of Pharmacy, Shinagawa, Tokyo, 142-8555, Japan) ,  Yamamoto Shinichiro (Division of Pharmacology, Faculty of Pharmaceutical Sciences, Teikyo Heisei University, Nakano, Tokyo, 164-8530, Japan) ,  Mori Yasuo (Department of Synthetic Chemistry and Biological Chemistry, Graduate School of Engineering, Kyoto University, Kyoto, 615-8510, Japan) ,  Shimizu Shunichi (Division of Pharmacology, Faculty of Pharmaceutical Sciences, Teikyo Heisei University, Nakano, Tokyo, 164-8530, Japan)
Material： European Journal of Pharmacology  (Eur J Pharmacol)
Volume： 891  Page： Null  Publication year： 2021 
JST Material Number： B0841A  ISSN： 0014-2999  CODEN： EJPHAZ  Document type： Article
Article type： 原著論文  Country of issue： Netherlands (NLD)  Language： ENGLISH (EN)

Abstract/Point： Transient receptor potential m...

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Thesaurus term： electric potential ,  sensitivity ,  antitumor drug ,  *bone marrow ,  receptor ,  leukopenia ,  human(primates) ,  side effect ,  colony(community) ,  channel ,  myeloid cell ,  wild type ,  cell death ,  oxidative stress
Semi thesaurus term： *骨髄抑制 , 【Automatic Indexing@JST】

Author keywords (5)： TRPM2 ,  Myelosuppression ,  5-Fluorouracil ,  Oxidative stress ,  Bone marrow

JST classification (2)： Cell physiology in general  (EF02010S) ,  Transport of cell membrane  (EF04020R)

Terms in the title (7)： マウス ,  5-フルオロウラシル ,  誘発 ,  骨髄抑制 ,  TRPM2 ,  活性化 ,  可能性