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J-GLOBAL ID：202102241665877968   Reference number：21A0015056

Biologically Active TNIIIA2 Region in Tenascin-C Molecule: A Major Contributor to Elicit Aggressive Malignant Phenotypes From Tumors/Tumor Stroma

テネイシンC分子における生物活性TNIIIA2領域:腫瘍/腫瘍間質からの攻撃的悪性表現型を誘発するMajor寄与因子【JST・京大機械翻訳】

Author (3)： Iyoda Takuya (1Department of Pharmacy, Faculty of Pharmaceutical Sciences, Sanyo-Onoda City University, Sanyo-Onoda, Japan) ,  Fujita Motomichi (2Department of Molecular Patho-Physiology, Faculty of Pharmaceutical Sciences, Tokyo University of Science, Noda, Japan) ,  Fukai Fumio (2Department of Molecular Patho-Physiology, Faculty of Pharmaceutical Sciences, Tokyo University of Science, Noda, Japan)
Material： Frontiers in Immunology (Web)
Volume： 11  Page： 610096  Publication year： 2020 
JST Material Number： U7074A  ISSN： 1664-3224  Document type： Article
Article type： 文献レビュー  Country of issue： Switzerland (CHE)  Language： ENGLISH (EN)

Abstract/Point： Tenascin (TN)-C is highly expr...

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Thesaurus term： peptide ,  inflammation ,  *tumor ,  *phenotype ,  *biological activity ,  cell adhesion ,  macrophage ,  fibronectin ,  targeting ,  up-regulation ,  integrin ,  glioblastoma
Semi thesaurus term： 悪性腫瘍 ,  腫瘍進行 ,  インテグリンβ1 , 【Automatic Indexing@JST】

Author keywords (7)： tenascin-C ,  TNIIIA2 ,  β1-integrin ,  macrophage ,  solid tumor ,  glioblastoma ,  PDGF

JST classification (3)： Chemistry,biochemistry and pathology of tumors(=neoplasms)  (GE02030N) ,  Biological function  (EB03040U) ,  Cell physiology in general  (EF02010S)

Reference (87)：

• Chiquet-EhrismannRMackieEJPearsonCASakakuraT. Tenascin: an extracellular matrix protein involved in tissue interactions during fetal development and oncogenesis. Cell (1986) 47:131-9. doi: doi: 10.1016/0092-8674(86)90374-0
• LightnerVASlempCAEricksonHP. Localization and quantitation of hexabrachion (tenascin) in skin, embryonic brain, tumors, and plasma. Ann N Y Acad Sci (1990) 580:260-75. doi: doi: 10.1111/j.1749-6632.1990.tb17935.x
• Chiquet-EhrismannRChiquetM. Tenascins: regulation and putative functions during pathological stress. J Pathol (2003) 200:488-99. doi: doi: 10.1002/path.1415
• OrendGChiquet-EhrismannR. Tenascin-C induced signaling in cancer. Cancer Lett (2006) 244:143-63. doi: doi: 10.1016/j.canlet.2006.02.017
• MidwoodKSHussenetTLangloisBOrendG. Advances in tenascin-C biology. Cell Mol Life Sci (2011) 68:3175-99. doi: doi: 10.1007/s00018-011-0783-6

Terms in the title (10)： テネイシンC ,  分子 ,  生物活性 ,  TNIIIA2 ,  腫瘍 ,  腫瘍間質 ,  攻撃 ,  表現型 ,  誘発 ,  因子