Art

J-GLOBAL ID：202102243600666074   Reference number：21A0096168

Podoplanin is indispensable for cell motility and platelet-induced epithelial-to-mesenchymal transition-related gene expression in esophagus squamous carcinoma TE11A cells

ポドプラニンは,食道扁平上皮癌TE11A細胞における細胞運動性および血小板誘発上皮間葉転換関連遺伝子発現に不可欠である【JST・京大機械翻訳】

Author (15)： Watanabe Nobuo (Department of Emergency and Critical Care Medicine, Tokai University School of Medicine, Isehara, Japan) ,  Kidokoro Masako (Department of Emergency and Critical Care Medicine, Tokai University School of Medicine, Isehara, Japan) ,  Tanaka Makiko (Department of Emergency and Critical Care Medicine, Tokai University School of Medicine, Isehara, Japan) ,  Inoue Shigeaki (Department of Emergency and Critical Care Medicine, Tokai University School of Medicine, Isehara, Japan) ,  Tsuji Tomoatsu (Department of Emergency and Critical Care Medicine, Tokai University School of Medicine, Isehara, Japan) ,  Akatuska Hisako (Department of Host Defense Mechanism, Tokai University School of Medicine, Isehara, Japan) ,  Okada Chisa (Support Center for Medical Research and Education, Tokai University, Isehara, Japan) ,  Iida Yumi (Support Center for Medical Research and Education, Tokai University, Isehara, Japan) ,  Okada Yoshinori (Support Center for Medical Research and Education, Tokai University, Isehara, Japan) ,  Suzuki Yusuke (Support Center for Medical Research and Education, Tokai University, Isehara, Japan) ,  Sato Takehito (Department of Host Defense Mechanism, Tokai University School of Medicine, Isehara, Japan) ,  Yahata Takashi (Research Center for Regenerative Medicine, Tokai University School of Medicine, Isehara, Japan) ,  Hirayama Noriaki (Institute of Advanced Biosciences, Tokai University, Hiratsuka, Japan) ,  Nakagawa Yoshihide (Department of Emergency and Critical Care Medicine, Tokai University School of Medicine, Isehara, Japan) ,  Inokuchi Sadaki (Department of Emergency and Critical Care Medicine, Tokai University School of Medicine, Isehara, Japan)
Material： Cancer Cell International (Web)
Volume： 20  Issue： 1  Page： 1-22  Publication year： 2020 
JST Material Number： U7315A  ISSN： 1475-2867  Document type： Article
Article type： 原著論文  Country of issue： United Kingdom (GBR)  Language： ENGLISH (EN)

Abstract/Point： The transmembrane glycoprotein...

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Thesaurus term： *gene ,  *thrombocyte ,  tumor ,  tumor cell ,  *epithelium ,  human ,  allele ,  Vimentin ,  *mesenchyme ,  *gene expression ,  Down-Regulation ,  biomarker ,  neutralizing antibody ,  *podoplanin ,  Signal Transduction ,  *membrane and film ,  *histomembrane ,  Proteins ,  *molecular genetic phenomenon
Semi thesaurus term： cellular signal transduction , 【Automatic Indexing@JST】

Author keywords (5)： Metastasis ,  Platelet ,  Esophageal squamous cell carcinoma ,  Crispr-Cas-9 ,  Knockdown

JST classification (1)： Chemistry,biochemistry and pathology of tumors(=neoplasms)  (GE02030N)

Reference (43)：

• Front Immunol; Podoplanin: emerging functions in development, the immune system, and cancer; JL Astarita, SE Acton, SJ Turley; 3; 2012; 283; citation_id=CR1
• Cancer Metastasis Rev; Platelet-activating factor podoplanin: from discovery to drug development; A Takemoto, K Miyata, N Fujita; 36; 2; 2017; 225-234; citation_id=CR2
• Int J Mol Sci; Podoplanin in inflammation and cancer; M Quintanilla, L Montero-Montero, J Renart, E Martin-Villar; 20; 2019; 3; citation_id=CR3
• Nature; Podoplanin maintains high endothelial venule integrity by interacting with platelet CLEC-2; BH Herzog, J Fu, SJ Wilson, PR Hess, A Sen, JM McDaniel, Y Pan, M Sheng, T Yago, R Silasi-Mansat; 502; 7469; 2013; 105-109; citation_id=CR4
• Mol Med Rep; Expression of podoplanin and vimentin is correlated with prognosis in esophageal squamous cell carcinoma; M Tanaka, H Kijima, H Shimada, H Makuuchi, S Ozawa, S Inokuchi; 12; 3; 2015; 4029-4036; citation_id=CR5

Terms in the title (8)： ポドプラニン ,  食道扁平上皮癌 ,  細胞 ,  細胞運動性 ,  血小板 ,  誘発 ,  上皮間葉転換 ,  遺伝子発現