Art

J-GLOBAL ID：202102245681372308   Reference number：21A0084068

Analysis of N6-Methyladenosine Methyltransferase Reveals METTL14 and ZC3H13 as Tumor Suppressor Genes in Breast Cancer

N6-メチルアデノシンメチルトランスフェラーゼの解析は乳癌における腫瘍抑制遺伝子としてMETTL14およびZC3H13を明らかにする【JST・京大機械翻訳】

Author (9)： Gong Peng-Ju (Department of Breast and Thyroid Surgery, Zhongnan Hospital, Hubei Key Laboratory of Tumor Biological Behaviors, Hubei Cancer Clinical Study Center, Wuhan University, Wuhan, China) ,  Shao You-Cheng (Department of Pathology and Pathophysiology, Hubei Provincial Key Laboratory of Developmentally Originated Disease, School of Basic Medical Sciences, Wuhan University, Wuhan, China) ,  Yang Yan (Department of Breast and Thyroid Surgery, Zhongnan Hospital, Hubei Key Laboratory of Tumor Biological Behaviors, Hubei Cancer Clinical Study Center, Wuhan University, Wuhan, China) ,  Song Wen-Jing (Department of Breast and Thyroid Surgery, Zhongnan Hospital, Hubei Key Laboratory of Tumor Biological Behaviors, Hubei Cancer Clinical Study Center, Wuhan University, Wuhan, China) ,  He Xin (Department of Breast and Thyroid Surgery, Zhongnan Hospital, Hubei Key Laboratory of Tumor Biological Behaviors, Hubei Cancer Clinical Study Center, Wuhan University, Wuhan, China) ,  Zeng Yi-Fan (Department of Breast and Thyroid Surgery, Zhongnan Hospital, Hubei Key Laboratory of Tumor Biological Behaviors, Hubei Cancer Clinical Study Center, Wuhan University, Wuhan, China) ,  Huang Si-Rui (Department of Breast and Thyroid Surgery, Zhongnan Hospital, Hubei Key Laboratory of Tumor Biological Behaviors, Hubei Cancer Clinical Study Center, Wuhan University, Wuhan, China) ,  Wei Lei (Department of Pathology and Pathophysiology, Hubei Provincial Key Laboratory of Developmentally Originated Disease, School of Basic Medical Sciences, Wuhan University, Wuhan, China) ,  Zhang Jing-Wei (Department of Breast and Thyroid Surgery, Zhongnan Hospital, Hubei Key Laboratory of Tumor Biological Behaviors, Hubei Cancer Clinical Study Center, Wuhan University, Wuhan, China)
Material： Frontiers in Oncology (Web)
Volume： 10  Page： 578963  Publication year： 2020 
JST Material Number： U7089A  ISSN： 2234-943X  Document type： Article
Article type： 原著論文  Country of issue： Switzerland (CHE)  Language： ENGLISH (EN)

Abstract/Point： Objectives: Recently, an incre...

Register(free) or Log In to access     To see more with JDream III (charged).   {{ this.onShowAbsJLink("http://jdream3.com/lp/jglobal/index.html?docNo=21A0084068&from=J-GLOBAL&jstjournalNo=U7089A") }}

Thesaurus term： immersional wetting ,  biosynthesis ,  methylation ,  *tumor ,  tumor cell ,  *transferase ,  carcinogenesis ,  macrophage ,  prognosis ,  neutrophils ,  tumor invasion ,  *breast tumor
Semi thesaurus term： 予後不良 ,  腫瘍進行 ,  アンタゴニスト , 【Automatic Indexing@JST】

Author keywords (7)： m6A ,  METTL14 ,  ZC3H13 ,  breast cancer ,  prognosis ,  APC ,  Wnt signaling pathway

JST classification (2)： Carcinogenic mechanisms and factors  (GE02020C) ,  Gene expression  (EC02040Q)

Reference (51)：

• EstevaFJHubbard-LuceyVMTangJPusztaiL. Immunotherapy and targeted therapy combinations in metastatic breast cancer. Lancet Oncol (2019) 20(3):e175-86. doi: doi: 10.1016/S1470-2045(19)30026-9
• ArnedosMVicierCLoiSLefebvreCMichielsSBonnefoiH. Precision medicine for metastatic breast cancer-limitations and solutions. Nat Rev Clin Oncol (2015) 12(12):693-704. doi: doi: 10.1038/nrclinonc.2015.123
• GeRWangZMontironiRJiangZChengMSantoniM. Epigenetic modulations and lineage plasticity in advanced prostate cancer. Ann Oncol (2020) 31(4):470-9. doi: doi: 10.1016/j.annonc.2020.02.002
• BylerSGoldgarSHeerbothSLearyMHousmanGMoultonK. Genetic and epigenetic aspects of breast cancer progression and therapy. Anticancer Res (2014) 34(3):1071-7.
• DesrosiersRFridericiKRottmanF. Identification of methylated nucleosides in messenger RNA from Novikoff hepatoma cells. Proc Natl Acad Sci U S A (1974) 71(10):3971-5. doi: doi: 10.1073/pnas.71.10.3971

Terms in the title (3)： 解析 ,  乳癌 ,  腫瘍抑制遺伝子