Art

J-GLOBAL ID：202102253139671609   Reference number：21A0328545

A newly developed age estimation method based on CpG methylation of teeth-derived DNA using real-time methylation-specific PCR

リアルタイムメチル化特異的PCRを用いた歯由来DNAのCpGメチル化に基づく新たに開発した年齢推定法

Author (7)： Kondo Masahiro (Department of Legal Medicine, Nihon University School of Dentistry) ,  Aboshi Hirofumi (Department of Legal Medicine, Nihon University School of Dentistry) ,  Yoshikawa Masaaki (Division of Anatomical Science, Department of Functional Morphology, Nihon University School of Medicine) ,  Ogata Ayano (Department of Legal Medicine, Nihon University School of Dentistry) ,  Murayama Ryosuke (Department of Legal Medicine, Nihon University School of Dentistry) ,  Takei Masami (Division of Hematology and Rheumatology, Department of Medicine, Nihon University School of Medicine) ,  Aizawa Shin (Division of Anatomical Science, Department of Functional Morphology, Nihon University School of Medicine)
Material： Journal of Oral Science  (J Oral Sci)
Volume： 63  Issue： 1  Page： 54-58(J-STAGE)  Publication year： 2021 
JST Material Number： Z0759A  ISSN： 1343-4934  Document type： Article
Article type： 原著論文  Country of issue： Japan (JPN)  Language： ENGLISH (EN)

Thesaurus term： human ,...
Semi thesaurus term： dead body ,...

Register(free) or Log In to access     To see more with JDream III (charged).   {{ this.onShowAbsJLink("http://jdream3.com/lp/jglobal/index.html?docNo=21A0328545&from=J-GLOBAL&jstjournalNo=Z0759A") }}

Author keywords (6)： age estimation ,  bisulfite conversion ,  CpG islands ,  DNA methylation ,  ELOVL2 ,  forensic age

JST classification (1)： Clinical dentistry(= odontology)in general  (GT01030Z)

Reference (37)：

• 1. Vidaki A, Daniel B, Court DS (2013) Forensic DNA methylation profiling- potential opportunities and challenges. Forensic Sci Int Genet 7, 499-507.
• 2. Kader F, Ghai M (2015) DNA methylation and application in forensic sciences. Forensic Sci Int 249, 255-265.
• 3. Johnson TE (2006) Recent results: biomarkers of aging. Exp Gerontol 41, 1243-1246.
• 4. Alkass K, Buchholz BA, Ohtani S, Yamamoto T, Druid H, Spalding KL (2010) Age estimation in forensic sciences: application of combined aspartic acid racemization and radiocarbon analysis. Mol Cell Proteomics 9, 1022-1030.
• 5. Deaton A, Brid A (2011) CpG islands and the regulation of transcription. Genes Dev 25, 1010-1022.

Terms in the title (8)： リアルタイム ,  メチル化 ,  PCR ,  歯 ,  DNA ,  CpGメチル化 ,  開発 ,  年齢推定