Art

J-GLOBAL ID：202102257621986933   Reference number：21A0375689

Total synthesis of (±)-spirotenuipesine A, a promoter of neurotrophic factor secretion from glial cells

グリア細胞からの神経栄養因子分泌のプロモーターである(±)-スピロテヌイペシンAの全合成【JST・京大機械翻訳】

Author (7)： Yanagimoto Tsuyoshi (Chemistry of Functional Molecule, Faculty of Pharmaceutical Sciences, Tokushima Bunri University, 180 Nishihamabouji Yamashiro-cyo, Tokushima 770-8514, Japan) ,  Yamada Sayo (Chemistry of Functional Molecule, Faculty of Pharmaceutical Sciences, Tokushima Bunri University, 180 Nishihamabouji Yamashiro-cyo, Tokushima 770-8514, Japan) ,  Kasai Yusuke (Chemistry of Functional Molecule, Faculty of Pharmaceutical Sciences, Tokushima Bunri University, 180 Nishihamabouji Yamashiro-cyo, Tokushima 770-8514, Japan) ,  Yamamoto Hirofumi (Institute of Pharmacognosy, Tokushima Bunri University, 180 Nishihamabouji Yamashiro-cyo, Tokushima 770-8514, Japan) ,  Kubo Miwa (Chemistry of Natural Products, Faculty of Pharmaceutical Sciences, Tokushima Bunri University, 180 Nishihamabouji Yamashiro-cyo, Tokushima 770-8514, Japan) ,  Fukuyama Yoshiyasu (Chemistry of Natural Products, Faculty of Pharmaceutical Sciences, Tokushima Bunri University, 180 Nishihamabouji Yamashiro-cyo, Tokushima 770-8514, Japan) ,  Imagawa Hiroshi (Chemistry of Functional Molecule, Faculty of Pharmaceutical Sciences, Tokushima Bunri University, 180 Nishihamabouji Yamashiro-cyo, Tokushima 770-8514, Japan)
Material： Tetrahedron Letters  (Tetrahedron Lett)
Volume： 64  Page： Null  Publication year： 2021 
JST Material Number： E0366A  ISSN： 0040-4039  Document type： Article
Article type： 短報  Country of issue： United Kingdom (GBR)  Language： ENGLISH (EN)

Abstract/Point： Naturally occurring (+)-spirot...

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Thesaurus term： biosynthesis ,  Ireland ,  *total synthesis ,  *promoter(genetics) ,  *glia cell ,  spontaneous generation ,  racemic modification ,  Alzheimer disease ,  *neurotrophic factor ,  PC12 cell
Semi thesaurus term： 神経変性疾患 ,  分化誘導 ,  軸索成長 ,  生物学的評価 , 【Automatic Indexing@JST】

Author keywords (5)： Spirotenuipesine ,  Neurotrophic factor ,  Neurite outgrowth ,  PC12 cells ,  1321Nl cells

JST classification (3)： Basic research of antitumor(=antineoplastic)drugs  (GW16010A) ,  Plant biochemistry  (EH01050J) ,  Synthesis of drugs  (GV01030F)

Terms in the title (6)： グリア細胞 ,  神経栄養因子 ,  分泌 ,  プロモーター ,  スピロテヌイペシンA ,  全合成