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J-GLOBAL ID：202102258909266353   Reference number：21A0423210

Activation of β2-adrenergic receptor signals suppresses mesenchymal phenotypes of oral squamous cell carcinoma cells

β2アドレナリン受容体シグナルの活性化は口腔扁平上皮癌細胞の間葉系表現型を抑制する
Author (9)：
Sakakitani Shintaro

About Sakakitani Shintaro

(Department of Oral and Maxillofacial Surgery, Graduate School of Medical and Dental Sciences, Tokyo Medical and Dental University (TMDU), Tokyo, Japan)

About Department of Oral and Maxillofacial Surgery, Graduate School of Medical and Dental Sciences, Tokyo Medical and Dental University (TMDU), Tokyo, Japan

, 
Sakakitani Shintaro

About Sakakitani Shintaro

(Department of Biochemistry, Graduate School of Medical and Dental Sciences, Tokyo Medical and Dental University (TMDU), Tokyo, Japan)

About Department of Biochemistry, Graduate School of Medical and Dental Sciences, Tokyo Medical and Dental University (TMDU), Tokyo, Japan

, 
Podyma-Inoue Katarzyna A.

About Podyma-Inoue Katarzyna A.

(Department of Biochemistry, Graduate School of Medical and Dental Sciences, Tokyo Medical and Dental University (TMDU), Tokyo, Japan)

About Department of Biochemistry, Graduate School of Medical and Dental Sciences, Tokyo Medical and Dental University (TMDU), Tokyo, Japan

, 
Takayama Rina

About Takayama Rina

(Department of Biochemistry, Graduate School of Medical and Dental Sciences, Tokyo Medical and Dental University (TMDU), Tokyo, Japan)

About Department of Biochemistry, Graduate School of Medical and Dental Sciences, Tokyo Medical and Dental University (TMDU), Tokyo, Japan

, 
Takahashi Kazuki

About Takahashi Kazuki

(Department of Biochemistry, Graduate School of Medical and Dental Sciences, Tokyo Medical and Dental University (TMDU), Tokyo, Japan)

About Department of Biochemistry, Graduate School of Medical and Dental Sciences, Tokyo Medical and Dental University (TMDU), Tokyo, Japan

, 
Ishigami-Yuasa Mari

About Ishigami-Yuasa Mari

(Department of Organic and Medicinal Chemistry, Chemical Biology Screening Center, Institute of Biomaterials and Bioengineering, Tokyo Medical and Dental University (TMDU), Tokyo, Japan)

About Department of Organic and Medicinal Chemistry, Chemical Biology Screening Center, Institute of Biomaterials and Bioengineering, Tokyo Medical and Dental University (TMDU), Tokyo, Japan

, 
Kagechika Hiroyuki

About Kagechika Hiroyuki

(Department of Organic and Medicinal Chemistry, Chemical Biology Screening Center, Institute of Biomaterials and Bioengineering, Tokyo Medical and Dental University (TMDU), Tokyo, Japan)

About Department of Organic and Medicinal Chemistry, Chemical Biology Screening Center, Institute of Biomaterials and Bioengineering, Tokyo Medical and Dental University (TMDU), Tokyo, Japan

, 
Harada Hiroyuki

About Harada Hiroyuki

(Department of Oral and Maxillofacial Surgery, Graduate School of Medical and Dental Sciences, Tokyo Medical and Dental University (TMDU), Tokyo, Japan)

About Department of Oral and Maxillofacial Surgery, Graduate School of Medical and Dental Sciences, Tokyo Medical and Dental University (TMDU), Tokyo, Japan

, 
Watabe Tetsuro

About Watabe Tetsuro

(Department of Biochemistry, Graduate School of Medical and Dental Sciences, Tokyo Medical and Dental University (TMDU), Tokyo, Japan)

About Department of Biochemistry, Graduate School of Medical and Dental Sciences, Tokyo Medical and Dental University (TMDU), Tokyo, Japan


Material：
Cancer Science (Web)  (Cancer Sci (Web))

About Cancer Science (Web)


Volume： 112  Issue： 1  Page： 155-167  Publication year： 2021 
JST Material Number： U0505A  ISSN： 1349-7006  Document type： Article
Article type： 原著論文  Country of issue： United States (USA)  Language： ENGLISH (EN)
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tumor cell

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CRISPR-Cas9 system

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Author keywords (5)：
β2-adrenergic receptor

About β2-adrenergic receptor

, 
isoxsuprine

About isoxsuprine

, 
MET (mesenchymal-epithelial transition)

About MET (mesenchymal-epithelial transition)

, 
oral squamous cell carcinoma

About oral squamous cell carcinoma

, 
tumor growth

About tumor growth

JST classification (2)：
JST classification
Category name(code) classified by JST.
Chemistry,biochemistry and pathology of tumors(=neoplasms) 
(GE02030N)

About Chemistry,biochemistry and pathology of tumors(=neoplasms)

,  Receptors on cell membrane 
(EF04030C)

About Receptors on cell membrane

Substance index (1)：
Substance index
Chemical Substance indexed to the Article.
Isoxsuprine

About Isoxsuprine

Terms in the title (6)：
Terms in the title
Keywords automatically extracted from the title.
β2アドレナリン受容体

About β2アドレナリン受容体

, 
シグナル

About シグナル

, 
活性化

About 活性化

, 
口腔扁平上皮癌細胞

About 口腔扁平上皮癌細胞

, 
間葉

About 間葉

, 
表現型

About 表現型


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