Art

J-GLOBAL ID：202102266628089443   Reference number：21A0038344

Site-specific ubiquitination of the E3 ligase HOIP regulates apoptosis and immune signaling

E3リガーゼHOIPの部位特異的ユビキチン化はアポトーシスおよび免疫シグナリングを調節する【JST・京大機械翻訳】

Author (15)： Fennell Lilian M (Institute of Molecular Biotechnology of the Austrian Academy of Sciences (IMBA), Vienna Biocenter (VBC), Vienna, Austria) ,  Gomez Diaz Carlos (Institute of Molecular Biotechnology of the Austrian Academy of Sciences (IMBA), Vienna Biocenter (VBC), Vienna, Austria) ,  Deszcz Luiza (Institute of Molecular Biotechnology of the Austrian Academy of Sciences (IMBA), Vienna Biocenter (VBC), Vienna, Austria) ,  Kavirayani Anoop (Vienna Biocenter Core Facilities (VBCF), Vienna Biocenter (VBC), Vienna, Austria) ,  Hoffmann David (Institute of Molecular Biotechnology of the Austrian Academy of Sciences (IMBA), Vienna Biocenter (VBC), Vienna, Austria) ,  Yanagitani Kota (Medical Institute of Bioregulation (MIB), Kyushu University, Fukuoka, Japan) ,  Schleiffer Alexander (Institute of Molecular Biotechnology of the Austrian Academy of Sciences (IMBA), Vienna Biocenter (VBC), Vienna, Austria) ,  Schleiffer Alexander (Research Institute of Molecular Pathology (IMP), Vienna Biocenter (VBC), Vienna, Austria) ,  Mechtler Karl (Institute of Molecular Biotechnology of the Austrian Academy of Sciences (IMBA), Vienna Biocenter (VBC), Vienna, Austria) ,  Mechtler Karl (Research Institute of Molecular Pathology (IMP), Vienna Biocenter (VBC), Vienna, Austria) ,  Hagelkruys Astrid (Institute of Molecular Biotechnology of the Austrian Academy of Sciences (IMBA), Vienna Biocenter (VBC), Vienna, Austria) ,  Penninger Josef (Institute of Molecular Biotechnology of the Austrian Academy of Sciences (IMBA), Vienna Biocenter (VBC), Vienna, Austria) ,  Penninger Josef (Department of Medical Genetics, Life Sciences Institute, University of British Columbia, Vancouver, BC, Canada) ,  Ikeda Fumiyo (Institute of Molecular Biotechnology of the Austrian Academy of Sciences (IMBA), Vienna Biocenter (VBC), Vienna, Austria) ,  Ikeda Fumiyo (Medical Institute of Bioregulation (MIB), Kyushu University, Fukuoka, Japan)
Material： EMBO Journal  (EMBO J)
Volume： 39  Issue： 24  Page： e103303  Publication year： 2020 
JST Material Number： A0911B  ISSN： 0261-4189  CODEN： EMJODG  Document type： Article
Article type： 原著論文  Country of issue： United States (USA)  Language： ENGLISH (EN)

Abstract/Point： HOIP, the catalytic component ...

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Thesaurus term： interaction ,  inflammation ,  human(primates) ,  phenotype ,  complex(substance) ,  *ubiquitin ,  TNF ,  wild type ,  cellular signal transduction ,  *apoptosis ,  NF-kappaB ,  *ubiquitination
Semi thesaurus term： TNF受容体I ,  ノックインマウス ,  LUBAC , 【Automatic Indexing@JST】

Author keywords (5)： apoptosis ,  HOIP E3 ligase ,  linear ubiquitination ,  skin inflammation ,  TNF

JST classification (1)： Cell physiology in general  (EF02010S)

Terms in the title (6)： E3リガーゼ ,  ユビキチン化 ,  アポトーシス ,  免疫 ,  シグナリング ,  調節