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J-GLOBAL ID：202102270117987238   Reference number：21A2577571

The Impact of Single Nucleotide Polymorphism in the Long Non-coding MEG3 Gene on MicroRNA-182 and MicroRNA-29 Expression Levels in the Development of Breast Cancer in Egyptian Women

エジプト女性の乳癌発症におけるマイクロRNA-182およびマイクロRNA-29発現レベルに及ぼす長鎖非コードMEG3遺伝子における単一ヌクレオチド多型の影響【JST・京大機械翻訳】

Author (3)： Shaker Olfat (Medical Biochemistry and Molecular Biology Department, Kasr Al Ainy Hospital, Faculty of Medicine, Cairo University, Cairo, Egypt) ,  Ayeldeen Ghada (Medical Biochemistry and Molecular Biology Department, Kasr Al Ainy Hospital, Faculty of Medicine, Cairo University, Cairo, Egypt) ,  Abdelhamid Amr (Biochemistry Department, Faculty of Pharmacy, October University for Modern Sciences and Arts, 6th of October City, Egypt)
Material： Frontiers in Genetics (Web)
Volume： 12  Page： 683809  Publication year： 2021 
JST Material Number： U7071A  ISSN： 1664-8021  Document type： Article
Article type： 原著論文  Country of issue： Switzerland (CHE)  Language： ENGLISH (EN)

Abstract/Point： Early-stage detection of BC is...

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Thesaurus term： *RNA ,  *gene ,  genotype ,  serum ,  survival ratio ,  allele ,  *long chain ,  *breast tumor ,  biomarker ,  *single nucleotide polymorphism ,  quantitative polymerase chain reaction
Semi thesaurus term： *マイクロRNA ,  非翻訳RNA ,  内因性 ,  標的遺伝子 , 【Automatic Indexing@JST】

Author keywords (5)： miRNAs ,  lncRNAs ,  MEG3 ,  BC ,  SNP

JST classification (2)： Chemistry,biochemistry and pathology of tumors(=neoplasms)  (GE02030N) ,  Gene expression  (EC02040Q)

Reference (38)：

• Ali M. A., Shaker O. G., Alazrak M., AbdelHafez M. N., Khalefa A. A., Hemeda N. F., et al. (2020). Association analyses of a genetic variant in long non-coding RNA MEG3 with breast cancer susceptibility and serum MEG3 expression level in the Egyptian population. Cancer Biomark 28, 49-63. doi: 10.3233/CBM-191072
• Bayarmaa B., Wu Z., Peng J., Wang Y., Xu S., Yan T., et al. (2019). Association of LncRNA MEG3 polymorphisms with efficacy of neoadjuvant chemotherapy in breast cancer. BMC Cancer 19:877. doi: 10.1186/s12885-019-6077-3
• Bhat A. A., Younes S. N., Raza S. S., Zarif L., Nisar S., Ahmed I., et al. (2020). Role of non-coding RNA networks in leukemia progression, metastasis and drug resistance. Mol. Cancer 19, 1-21. doi: 10.1186/s12943-020-01175-9
• Braconi C., Kogure T., Valeri N., Huang N., Nuovo G., Costinean S., et al. (2011). microRNA-29 can regulate expression of the long non-coding RNA gene MEG3 in hepatocellular cancer. Oncogene 30, 4750-4756. doi: 10.1038/onc.2011.193
• Cao X., Zhuang S., Hu Y., Xi L., Deng L., Sheng H., et al. (2016). Associations between polymorphisms of long non-coding RNA MEG3 and risk of colorectal cancer in Chinese. Oncotarget 7, 19054-19059. doi: 10.18632/oncotarget.7764

Terms in the title (9)： エジプト ,  女性 ,  乳癌 ,  発症 ,  マイクロRNA-29 ,  発現 ,  長鎖 ,  遺伝子 ,  単一ヌクレオチド多型