Art

J-GLOBAL ID：202102272670386393   Reference number：21A0376141

Exploring mutable conserved sites and fatal non-conserved sites by random mutation of esterase from Sulfolobus tokodaii and subtilisin from Thermococcus kodakarensis

Thermococcus kodakarensisからのSulfolobus tokodaiiとスブチリシンからのエステラーゼのランダム変異による変異保存部位と致死非保存部位の探索【JST・京大機械翻訳】

Author (7)： Tanaka Shun-ichi (Department of Biomolecular Chemistry, Kyoto Prefectural University, Hangi-cho, Shimogamo, Sakyo-ku, Kyoto 606-8522, Japan) ,  Tsutaki Minami (Department of Biomolecular Chemistry, Kyoto Prefectural University, Hangi-cho, Shimogamo, Sakyo-ku, Kyoto 606-8522, Japan) ,  Yamamoto Seira (Department of Biomolecular Chemistry, Kyoto Prefectural University, Hangi-cho, Shimogamo, Sakyo-ku, Kyoto 606-8522, Japan) ,  Mizutani Hayate (Department of Biomolecular Chemistry, Kyoto Prefectural University, Hangi-cho, Shimogamo, Sakyo-ku, Kyoto 606-8522, Japan) ,  Kurahashi Ryo (Department of Biomolecular Chemistry, Kyoto Prefectural University, Hangi-cho, Shimogamo, Sakyo-ku, Kyoto 606-8522, Japan) ,  Hirata Azumi (Department of Anatomy and Cell Biology, Osaka Medical College, Daigaku-machi, Takatsuki, Osaka 569-8686, Japan) ,  Takano Kazufumi (Department of Biomolecular Chemistry, Kyoto Prefectural University, Hangi-cho, Shimogamo, Sakyo-ku, Kyoto 606-8522, Japan)
Material： International Journal of Biological Macromolecules  (Int J Biol Macromol)
Volume： 170  Page： 343-353  Publication year： 2021 
JST Material Number： T0898A  ISSN： 0141-8130  CODEN： IJBMDR  Document type： Article
Article type： 原著論文  Country of issue： Netherlands (NLD)  Language： ENGLISH (EN)

Abstract/Point： Homologous proteins differ in ...

Register(free) or Log In to access     To see more with JDream III (charged).   {{ this.onShowAbsJLink("http://jdream3.com/lp/jglobal/index.html?docNo=21A0376141&from=J-GLOBAL&jstjournalNo=T0898A") }}

Thesaurus term： Amino Acid Sequence ,  *ester bond hydrolase ,  *subtilisin ,  Proteins ,  Mutation ,  active site ,  binding site ,  Protein Engineering ,  Amino Acid Substitution ,  domain structure ,  propeptide ,  *Sulfolobus tokodaii ,  *Thermococcus kodakaraensis ,  *Sulfolobus ,  *Thermococcus ,  *microorganism ,  *Bacteria
Semi thesaurus term： *Sulfolobus ,  *Thermococcus , 【Automatic Indexing@JST】

Author keywords (3)： Protein engineering ,  Sequence alignment ,  Mutant protein

JST classification (3)： Enzyme in general  (EB09010D) ,  Gene manipulation  (EC02050B) ,  Molecular genetics in general  (EC02010J)

Terms in the title (7)： Thermococcus ,  Sulfolobus ,  スブチリシン ,  エステラーゼ ,  変異 ,  保存 ,  探索