Art

J-GLOBAL ID：202102273400582760   Reference number：21A0017538

Vitamin D deficiency exacerbates bleomycin-induced pulmonary fibrosis partially through aggravating TGF-β/Smad2/3-mediated epithelial-mesenchymal transition

ビタミンD欠乏はTGF-β/Smad2/3仲介上皮間葉転換を悪化してブレオマイシン誘発肺線維症を悪化させる【JST・京大機械翻訳】

Author (8)： Li Se-Ruo (Second Affiliated Hospital, Anhui Medical University, Hefei, China) ,  Tan Zhu-Xia (Second Affiliated Hospital, Anhui Medical University, Hefei, China) ,  Chen Yuan-Hua (Department of Toxicology, Anhui Medical University, Hefei, China) ,  Hu Biao (Second Affiliated Hospital, Anhui Medical University, Hefei, China) ,  Zhang Cheng (Department of Toxicology, Anhui Medical University, Hefei, China) ,  Wang Hua (Department of Toxicology, Anhui Medical University, Hefei, China) ,  Zhao Hui (Second Affiliated Hospital, Anhui Medical University, Hefei, China) ,  Xu De-Xiang (Department of Toxicology, Anhui Medical University, Hefei, China)
Material： Respiratory Research (Web)
Volume： 20  Issue： 1  Page： 1-11  Publication year： 2019 
JST Material Number： U7545A  ISSN： 1465-993X  Document type： Article
Article type： 原著論文  Country of issue： United Kingdom (GBR)  Language： ENGLISH (EN)

Abstract/Point： Our earlier report indicated t...

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Thesaurus term： gene ,  serum ,  collagen ,  *epithelium ,  dyeing ,  *bleomycin ,  *vitamin D deficiency ,  *pulmonary fibrosis ,  deposition ,  vimentin ,  cellular signal transduction ,  *TGF beta
Semi thesaurus term： *Smad2蛋白質 ,  Smad3蛋白質 ,  *上皮間葉転換 , 【Automatic Indexing@JST】

Author keywords (5)： Pulmonary fibrosis ,  Vitamin D deficiency ,  Epithelial-mesenchymal transition ,  Bleomycin ,  Mice

JST classification (1)： Basic medicine on respiratory system  (GI01020H)

Reference (39)：

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• Am. J. Pathol; The pathogenesis of bleomycin-induced pulmonary fibrosis in mice; IY Adamson, DH Bowden; 77; 2; 1974; 185-197; citation_id=CR4
• Toxicology Letters; Phenyl butyric acid inhibits epithelial-mesenchymal transition during bleomycin-induced lung fibrosis; H Zhao, HY Qin, LF Cao, YH Chen, ZX Tan, C Zhang; 232; 1; 2015; 213-220; 10.1016/j.toxlet.2014.10.013; citation_id=CR5

Terms in the title (9)： ビタミンD欠乏 ,  TGF-β ,  Smad2 ,  仲介 ,  上皮間葉転換 ,  悪化 ,  ブレオマイシン ,  誘発 ,  肺線維症