Art

J-GLOBAL ID：202102275189210221   Reference number：21A0096976

Identification of a novel IL-5 signaling pathway in chronic pancreatitis and crosstalk with pancreatic tumor cells

慢性膵炎における新規IL-5シグナル伝達経路の同定と膵臓腫瘍細胞とのクロストーク【JST・京大機械翻訳】

Author (12)： Gitto Sarah B. (Burnett School of Biomedical Sciences, College of Medicine, University of Central Florida, Orlando, USA) ,  Gitto Sarah B. (Present Address: Department of Pathology and Laboratory Medicine, Abramson Cancer Center, Perelman School of Medicine, University of Pennsylvania, Philadelphia, USA) ,  Beardsley Jordan M. (Burnett School of Biomedical Sciences, College of Medicine, University of Central Florida, Orlando, USA) ,  Nakkina Sai Preethi (Burnett School of Biomedical Sciences, College of Medicine, University of Central Florida, Orlando, USA) ,  Oyer Jeremiah L. (Burnett School of Biomedical Sciences, College of Medicine, University of Central Florida, Orlando, USA) ,  Cline Kathryn A. (Burnett School of Biomedical Sciences, College of Medicine, University of Central Florida, Orlando, USA) ,  Litherland Sally A. (AdventHealth Cancer Institute, Orlando, USA) ,  Copik Alicja J. (Burnett School of Biomedical Sciences, College of Medicine, University of Central Florida, Orlando, USA) ,  Khaled Amr S. (Orlando Veteran’s Affairs Medical Center, Orlando, USA) ,  Fanaian Na'im (AdventHealth Lab, Orlando, USA) ,  Arnoletti J. Pablo (AdventHealth Cancer Institute and Institute for Surgical Advancement, Orlando, USA) ,  Altomare Deborah A. (Burnett School of Biomedical Sciences, College of Medicine, University of Central Florida, Orlando, USA)
Material： Cell Communication and Signaling (Web)
Volume： 18  Issue： 1  Page： 1-14  Publication year： 2020 
JST Material Number： U7050A  ISSN： 1478-811X  Document type： Article
Article type： 原著論文  Country of issue： United Kingdom (GBR)  Language： ENGLISH (EN)

Abstract/Point： While inflammation is associat...

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Thesaurus term： inflammation ,  *tumor ,  *tumor cell ,  human(primates) ,  cytotoxicity ,  eosinophils ,  fibrous disease ,  *pancreatic tumor ,  *cellular signal transduction ,  *interleukin 5 ,  immunohistochemistry
Semi thesaurus term： 慢性炎症 ,  腫瘍進行 ,  微小環境 ,  免疫細胞 , 【Automatic Indexing@JST】

Author keywords (5)： Pancreatic ductal adenocarcinoma ,  Pancreatitis ,  IL-5 ,  IL-5R ,  Eosinophils

JST classification (2)： Tumors(=neoplasms)of digestive system  (GH04000D) ,  Chemistry,biochemistry and pathology of tumors(=neoplasms)  (GE02030N)

Reference (44)：

• Cancer Cell Int; Chemotherapy and tumor microenvironment of pancreatic cancer; Q Liu, Q Liao, Y Zhao; 17; 2017; 68; 10.1186/s12935-017-0437-3; citation_id=CR1
• J Clin Invest; Beta-catenin blocks Kras-dependent reprogramming of acini into pancreatic cancer precursor lesions in mice; JPt Morris, DA Cano, S Sekine, SC Wang, M Hebrok; 120; 2010; 508-520; 10.1172/JCI40045; citation_id=CR2
• Nature; Inflammation and cancer; LM Coussens, Z Werb; 420; 2002; 860-867; 10.1038/nature01322; citation_id=CR3
• Gut; Periacinar stellate shaped cells in rat pancreas: identification, isolation, and culture; MV Apte; 43; 1998; 128-133; 10.1136/gut.43.1.128; citation_id=CR4
• Cancers (Basel); Desmoplasia and chemoresistance in pancreatic cancer; M Schober; 6; 2014; 2137-2154; 10.3390/cancers6042137; citation_id=CR5

Terms in the title (7)： 慢性膵炎 ,  IL-5 ,  シグナル伝達経路 ,  同定 ,  膵臓腫瘍 ,  細胞 ,  クロストーク