Art

J-GLOBAL ID：202102277298280091   Reference number：21A0079169

Synthesis and biological activity of (±)-7,3′,4′-trihydroxyhomoisoflavan and its analogs

(±)-7,3→4,4→トリヒドロキシホモイソフラバンおよびその類似体の合成と生物活性【JST・京大機械翻訳】

Author (7)： Noshita Toshiro (Faculty of Life and Environmental Sciences, Prefectural University of Hiroshima, 5562 Nanatsuka, Shobara, Hiroshima 727-0023, Japan) ,  Noshita Toshiro (Department of Pharmacy, Gifu University of Medical Science, 4-3-3 Nijigaoka, Kani, Gifu 509-0293, Japan) ,  Fujita Kentaro (Program in Biological System Sciences, Graduate School of Comprehensive Scientific Research, Prefectural University of Hiroshima, 5562 Nanatsuka, Shobara, Hiroshima 727-0023, Japan) ,  Koga Takeru (Program in Biological System Sciences, Graduate School of Comprehensive Scientific Research, Prefectural University of Hiroshima, 5562 Nanatsuka, Shobara, Hiroshima 727-0023, Japan) ,  Ouchi Hidekazu (Department of Pharmacy, Faculty of Pharmacy, Kindai University, 3-4-1 Kowakae, Higashiosaka, Osaka 577-8502, Japan) ,  Tai Akihiro (Faculty of Life and Environmental Sciences, Prefectural University of Hiroshima, 5562 Nanatsuka, Shobara, Hiroshima 727-0023, Japan) ,  Tai Akihiro (Graduate School of Technology, Industrial and Social Sciences, Tokushima University, 2-1 Minami-Josanjima, Tokushima 770-8506, Japan)
Material： Bioorganic & Medicinal Chemistry Letters  (Bioorg Med Chem Lett)
Volume： 31  Page： Null  Publication year： 2021 
JST Material Number： W0248A  ISSN： 0960-894X  Document type： Article
Article type： 短報  Country of issue： Netherlands (NLD)  Language： ENGLISH (EN)

Abstract/Point： Acetylcholinesterase (AChE) in...

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Thesaurus term： Acetylcholinesterase ,  *biological activity ,  isoflavonoid ,  promoter (genetics) ,  analogical material ,  Alzheimer Disease ,  brain disease ,  Dracaena ,  axon growth ,  inhibitory activity ,  Nerve Growth Factor ,  factor ,  bioactive factor ,  growth factor ,  polyphenol ,  oxygen heterocyclic compound ,  polynuclear aromatic compound
Semi thesaurus term： NGF , 【Automatic Indexing@JST】

Author keywords (5)： Dragon’s blood ,  Homoisoflavan ,  AChE inhibitory activity ,  Neurite outgrowth promoting activity ,  Dracaena cambodiana

JST classification (2)： Basic research of enzyme preparations and enzyme inhibitor preparations  (GW21010W) ,  Basic research of other drugs acting on central nervous system  (GW03120U)

Substance index (2)： Catechol ,  Isofavan

Terms in the title (2)： 類似体 ,  生物活性