Art

J-GLOBAL ID：202102279025312533   Reference number：21A2327415

Dietary Fat and Protein Intake in Relation to Plasma Sphingolipids as Determined by a Large-Scale Lipidomic Analysis

大規模リピドミクス分析により決定された血漿スフィンゴ脂質に関連した食事脂肪と蛋白質摂取【JST・京大機械翻訳】

Author (16)： Seah Jowy Yi Hoong (Saw Swee Hock School of Public Health, National University of Singapore (NUS), Singapore 117549, Singapore) ,  Seah Jowy Yi Hoong (NUS Graduate School for Integrative Sciences and Engineering, NUS, Singapore 119077, Singapore) ,  Chew Wee Siong (Department of Pharmacology, Yong Loo Lin School of Medicine, NUS, Singapore 117600, Singapore) ,  Torta Federico (Department of Biochemistry, Yong Loo Lin School of Medicine, NUS, Singapore 117596, Singapore) ,  Torta Federico (Singapore Lipidomics Incubator, Life Sciences Institute, NUS, Singapore 117456, Singapore) ,  Khoo Chin Meng (Department of Medicine, Yong Loo Lin School of Medicine, NUS and National University Health System, Singapore 119228, Singapore) ,  Wenk Markus R. (Department of Biochemistry, Yong Loo Lin School of Medicine, NUS, Singapore 117596, Singapore) ,  Wenk Markus R. (Singapore Lipidomics Incubator, Life Sciences Institute, NUS, Singapore 117456, Singapore) ,  Herr Deron R. (Department of Pharmacology, Yong Loo Lin School of Medicine, NUS, Singapore 117600, Singapore) ,  Herr Deron R. (Department of Biology, San Diego State University, San Diego, CA 92182, USA) ,  Tai E. Shyong (Saw Swee Hock School of Public Health, National University of Singapore (NUS), Singapore 117549, Singapore) ,  Tai E. Shyong (Department of Medicine, Yong Loo Lin School of Medicine, NUS and National University Health System, Singapore 119228, Singapore) ,  Tai E. Shyong (Duke-NUS Graduate Medical School, Singapore 169857, Singapore) ,  Dam Rob M. van (Saw Swee Hock School of Public Health, National University of Singapore (NUS), Singapore 117549, Singapore) ,  Dam Rob M. van (NUS Graduate School for Integrative Sciences and Engineering, NUS, Singapore 119077, Singapore) ,  Dam Rob M. van (Department of Nutrition, Harvard T.H. Chan School of Public Health, Boston, MA 02115, USA)
Material： Metabolites (Web)
Volume： 11  Issue： 2  Page： 93  Publication year： 2021 
JST Material Number： U7243A  ISSN： 2218-1989  Document type： Article
Article type： 原著論文  Country of issue： Switzerland (CHE)  Language： ENGLISH (EN)

Abstract/Point： Sphingolipid concentrations ha...

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Thesaurus term： food ,  *plasma(blood) ,  plasma concentration ,  sphingomyelin ,  ceramide ,  *protein ,  *sphingolipid ,  long chain ,  type 2 diabetes mellitus
Semi thesaurus term： *食事性脂肪 ,  栄養摂取量 ,  栄養摂取 ,  *リピドミクス ,  飽和脂肪 ,  脂肪摂取量 , 【Automatic Indexing@JST】

Author keywords (8)： ceramides ,  hexosylceramides ,  lipidomics ,  monounsaturated fat ,  protein ,  polyunsaturated fat ,  saturated fat ,  sphingomyelin

JST classification (2)： Biochemistry of lipids in general  (EB05010B) ,  Metabolism and nutrition of lipids  (EJ02034Q)

Reference (42)：

• Chew, W.S.; Torta, F.; Ji, S.S.; Choi, H.; Begum, H.; Sim, X.; Khoo, C.M.; Khoo, E.Y.H.; Ong, W.Y.; Van Dam, R.M.; et al. Large-scale lipidomics identifies associations between plasma sphingolipids and T2DM incidence. JCI Insight 2019, 4, e126925.
• Seah, J.Y.H.; Chew, W.S.; Torta, F.; Khoo, C.M.; Wenk, M.R.; Herr, D.R.; Choi, H.; Tai, E.S.; van Dam, R.M. Plasma sphingolipids and risk of cardiovascular diseases: A large-scale lipidomic analysis. Metabolomics 2020, 16, 89.
• Lemaitre, R.N.; Fretts, A.M.; Sitlani, C.M.; Biggs, M.L.; Mukamal, K.; King, I.B.; Song, X.L.; Djousse, L.; Siscovick, D.S.; McKnight, B.; et al. Plasma phospholipid very-long-chain saturated fatty acids and incident diabetes in older adults: The Cardiovascular Health Study. Am. J. Clin. Nutr. 2015, 101, 1047-1054.
• Sigruener, A.; Kleber, M.E.; Heimerl, S.; Liebisch, G.; Schmitz, G.; Maerz, W. Glycerophospholipid and Sphingolipid Species and Mortality: The Ludwigshafen Risk and Cardiovascular Health (LURIC) Study. PLoS ONE 2014, 9, e85724.
• Mundra, P.A.; Barlow, C.K.; Nestel, P.J.; Barnes, E.H.; Kirby, A.; Thompson, P.; Sullivan, D.R.; Alshehry, Z.H.; Mellett, N.A.; Huynh, K.; et al. Large-scale plasma lipidomic profiling identifies lipids that predict cardiovascular events in secondary prevention. JCI Insight 2018, 3, e121326.

Terms in the title (7)： 大規模 ,  リピドミクス ,  分析 ,  血漿 ,  スフィンゴ脂質 ,  食事脂肪 ,  蛋白質