Art

J-GLOBAL ID：202102280994840501   Reference number：21A0099047

Recent advances in CAR-T cell engineering

CAR-T細胞工学における最近の進歩【JST・京大機械翻訳】

Author (11)： Huang Ruihao (Medical Center of Hematology, Xinqiao Hospital, State Key Laboratory of Trauma, Burn and Combined Injury, Army Medical University, Chongqing, China) ,  Li Xiaoping (Medical Center of Hematology, Xinqiao Hospital, State Key Laboratory of Trauma, Burn and Combined Injury, Army Medical University, Chongqing, China) ,  He Yundi (Medical Center of Hematology, Xinqiao Hospital, State Key Laboratory of Trauma, Burn and Combined Injury, Army Medical University, Chongqing, China) ,  Zhu Wen (Medical Center of Hematology, Xinqiao Hospital, State Key Laboratory of Trauma, Burn and Combined Injury, Army Medical University, Chongqing, China) ,  Gao Lei (Medical Center of Hematology, Xinqiao Hospital, State Key Laboratory of Trauma, Burn and Combined Injury, Army Medical University, Chongqing, China) ,  Liu Yao (Medical Center of Hematology, Xinqiao Hospital, State Key Laboratory of Trauma, Burn and Combined Injury, Army Medical University, Chongqing, China) ,  Gao Li (Medical Center of Hematology, Xinqiao Hospital, State Key Laboratory of Trauma, Burn and Combined Injury, Army Medical University, Chongqing, China) ,  Wen Qin (Medical Center of Hematology, Xinqiao Hospital, State Key Laboratory of Trauma, Burn and Combined Injury, Army Medical University, Chongqing, China) ,  Zhong Jiang F. (Department of Otolaryngology, Keck School of Medicine, University of Southern California, Los Angeles, USA) ,  Zhang Cheng (Medical Center of Hematology, Xinqiao Hospital, State Key Laboratory of Trauma, Burn and Combined Injury, Army Medical University, Chongqing, China) ,  Zhang Xi (Medical Center of Hematology, Xinqiao Hospital, State Key Laboratory of Trauma, Burn and Combined Injury, Army Medical University, Chongqing, China)
Material： Journal of Hematology & Oncology (Web)
Volume： 13  Issue： 1  Page： 1-19  Publication year： 2020 
JST Material Number： U7517A  ISSN： 1756-8722  Document type： Article
Article type： 文献レビュー  Country of issue： United Kingdom (GBR)  Language： ENGLISH (EN)

Abstract/Point： Chimeric antigen receptor T (C...

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Thesaurus term： immunotherapy ,  cytotoxicity ,  effectiveness ,  production technology ,  *cell transplantation
Semi thesaurus term： CD19抗原 ,  悪性腫瘍 ,  難治性腫瘍 ,  *細胞工学 ,  エクトドメイン ,  キメラ抗原受容体 , 【Automatic Indexing@JST】

Author keywords (3)： CAR-T cell therapy ,  Hematological malignancies ,  Immune therapy

JST classification (2)： Immunotherapy for tumors  (GE03035B) ,  Blood cell tumors(=neoplasms)  (GK04000M)

Reference (137)：

• J Hematol Oncol; CAR-T “the living drugs”, immune checkpoint inhibitors, and precision medicine: a new era of cancer therapy; D Liu; 12; 2019; 113; citation_id=CR1
• Lancet Oncol; CD19-directed CAR T cells gain traction; SJ Schuster; 20; 2019; 2-3; citation_id=CR2
• J Hematol Oncol; CD19 CAR-T cell therapy for relapsed/refractory acute lymphoblastic leukemia: factors affecting toxicities and long-term efficacies; L-N Zhang, Y Song, D Liu; 11; 2018; 41; citation_id=CR3
• Lancet Oncol.; Long-term safety and activity of axicabtagene ciloleucel in refractory large B-cell lymphoma (ZUMA-1): a single-arm, multicentre, phase 1-2 trial; FL Locke, A Ghobadi, CA Jacobson, DB Miklos, LJ Lekakis, OO Oluwole; 20; 2019; 31-42; citation_id=CR4
• N Engl J Med; Tisagenlecleucel in adult relapsed or refractory diffuse large B-cell lymphoma; SJ Schuster, MR Bishop, CS Tam, EK Waller, P Borchmann, JP McGuirk; 380; 2019; 45-56; citation_id=CR5

Terms in the title (2)： T細胞 ,  工学