Art

J-GLOBAL ID：202102288366649534   Reference number：21A0287067

Influence of MIF polymorphisms on CpG island hyper-methylation of CDKN2A in the patients with ulcerative colitis

潰瘍性大腸炎患者におけるCDKN2AのCpGアイランド高メチル化に対するMIF多型の影響【JST・京大機械翻訳】

Author (12)： Sakurai Naoko (Department of Gastroenterology, Kanazawa Medical University, Uchinada-machi, Japan) ,  Shibata Tomoyuki (Department of Gastroenterology, Fujita Health University, Toyoake, Japan) ,  Nakamura Masakatsu (Department of Gastroenterology, Kanazawa Medical University, Uchinada-machi, Japan) ,  Takano Hikaru (Department of Gastroenterology, Kanazawa Medical University, Uchinada-machi, Japan) ,  Hayashi Tasuku (Department of Gastroenterology, Kanazawa Medical University, Uchinada-machi, Japan) ,  Ota Masafumi (Department of Gastroenterology, Kanazawa Medical University, Uchinada-machi, Japan) ,  Nomura-Horita Tomoe (Department of Gastroenterology, Kanazawa Medical University, Uchinada-machi, Japan) ,  Hayashi Ranji (Department of Gastroenterology, Kanazawa Medical University, Uchinada-machi, Japan) ,  Shimasaki Takeo (Department of Gastroenterology, Kanazawa Medical University, Uchinada-machi, Japan) ,  Ostuka Toshimi (Department of Gastroenterology, Kanazawa Medical University, Uchinada-machi, Japan) ,  Tahara Tomomitsu (Department of Gastroenterology and Hepatology, Kansai Medical University, Osaka, Japan) ,  Arisawa Tomiyasu (Department of Gastroenterology, Kanazawa Medical University, Uchinada-machi, Japan)
Material： BMC Medical Genetics (Web)
Volume： 21  Issue： 1  Page： 1-9  Publication year： 2020 
JST Material Number： U7307A  ISSN： 1471-2350  Document type： Article
Article type： 原著論文  Country of issue： United Kingdom (GBR)  Language： ENGLISH (EN)

Abstract/Point： CDKN2A hypermethylation is amo...

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Thesaurus term： Regression Analysis ,  *Methylation ,  gene ,  Genotype ,  *Inflammation ,  Colon ,  mucosa ,  Carcinogenesis ,  allele ,  macrophage ,  remission ,  *ulcerative colitis ,  *CpG Islands ,  *CpG ,  hypermethylation ,  *ulcer ,  *symptom ,  *colitis (large intestine) ,  *Enteritis

Author keywords (5)： Ulcerative colitis ,  CDKN2A ,  CpG hypermethylation ,  Macrophage migration inhibitory factor ,  Genetic polymorphism

JST classification (3)： Digestive system diseases  (GH03000W) ,  Chemistry,biochemistry and pathology of tumors(=neoplasms)  (GE02030N) ,  Tumors(=neoplasms)of digestive system  (GH04000D)

Reference (43)：

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• Microb Infect; Macrophage migration inhibitory factor (MIF): mechanisms of action and role in disease; H Lue, R Kleemann, T Calandra, T Roger, J Bernhagen; 4; 2002; 449-460; 10.1016/S1286-4579(02)01560-5; citation_id=CR3
• Clin Exp Immunol; Macrophage migration inhibitory factor activates antigen-presenting dendritic cells and induces inflammatory cytokines in ulcerative colitis; H Murakami, SM Akbar, H Matsui, N Horiike, M Onji; 128; 2002; 504-510; 10.1046/j.1365-2249.2002.01838.x; citation_id=CR4
• Ann N Y Acad Sci; Macrophage migration inhibitory factor and activator protein-1 in ulcerative colitis; Y Ishiguro, K Yamagata, H Sakuraba, A Munakata, A Nakane, T Morita; 1029; 2004; 348-349; 10.1196/annals.1309.040; citation_id=CR5

Terms in the title (7)： 潰瘍性大腸炎 ,  患者 ,  CDKN2A ,  CpGアイランド ,  メチル化 ,  MIF ,  多型